Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17495238 | 0.87 | IKBKB (0.56) | ALDH1A1MAPK1IKBKBNPC1RAB9A | |
| SCHEMBL16219594 | 0.84 | HTR7 (0.41) | RAPGEF4CYP1A2 | |
| SCHEMBL17426506 | 0.84 | IKBKB (0.41) | ALDH1A1MAPK1RAPGEF4IKBKBNPC1 | |
| SCHEMBL6382163 | 0.82 | HTR7 (0.40) | RAPGEF4MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL17426508 | 0.81 | BIRC5 (0.43) | ALDH1A1MAPK1RAPGEF4IKBKBNPC1 | |
| SCHEMBL26032118 | 0.80 | ACHE (0.50) | ALDH1A1MAPK1NPC1RAB9AMEN1 | |
| SCHEMBL30818317 | 0.79 | IKBKB (0.50) | ALDH1A1MAPK1IKBKBNPC1RAB9A | |
| SCHEMBL24860528 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPK1RAPGEF4IKBKBNPC1 | |
| SCHEMBL20595546 | 0.78 | RAPGEF4 (0.38) | ALDH1A1MAPK1RAPGEF4NPC1RAB9A | |
| SCHEMBL23369619 | 0.78 | RAPGEF4 (0.38) | ALDH1A1MAPK1RAPGEF4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9174970-B2 | 5-fluoro pyrimidine derivatives | DOW AGROSCIENCES LLC (US) | 2015-11-03 | — | — | US | claimed |