Sugi Predict

Sugi Predict / Compounds / SCHEMBL17211152

SCHEMBL17211152

SCHEMBL17211152

CC1(C)c2ccccc2-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc5oc6ccccc6c5c4)c3)c21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 4/20 0.37
▸ PLA2G4A P47712 4/20 0.37
▸ PLA2G10 O15496 1/20 0.37
▸ HSP90AA1 P07900 1/20 0.37
▸ HSP90AB1 P08238 1/20 0.37
▸ CHEK2 O96017 1/20 0.35
▸ IDO1 P14902 3/20 0.34
▸ CASP3 P42574 1/20 0.33
▸ SENP7 Q9BQF6 1/20 0.33
▸ SENP6 Q9GZR1 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.32
▸ HPGD P15428 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ PRKDC P78527 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16746470 1.00 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL16746477 0.99 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL16746479 0.98 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL17211149 0.96 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL16746483 0.92 HSP90AA1 (0.35) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL16746475 0.91 PGR (0.39) HSP90AA1HSP90AB1CHEK2ALDH1A1HPGD
SCHEMBL16746214 0.89 ALOX5 (0.41) PLA2G2APLA2G4AALDH1A1HPGDKDM4E
SCHEMBL16746448 0.88 ALOX5 (0.43) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL16746417 0.88 ALOX5 (0.42) PLA2G2APLA2G4AALDH1A1MEN1MAPT
SCHEMBL16746455 0.88 ALOX5 (0.42) PLA2G2APLA2G4AALDH1A1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10790453-B2 Compounds and organic electronic device using the same LG CHEM, LTD. (KR) 2020-09-29 — — US disclosed
US-20170229659-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2017-08-10 — — US disclosed
US-20170229659-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2017-08-10 — — US disclosed
US-20150311450-A1 NEW COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2015-10-29 — — US disclosed
US-20150311450-A1 NEW COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2015-10-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150311450-A1 NEW COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING THE SAME VDAC2, VDAC3, VDAC1 PLA2G2A 3677/4885PLA2G4A 4299/4885PLA2G10 3733/4885
US-10790453-B2 Compounds and organic electronic device using the same VDAC2, EED, VDAC3 PLA2G2A 3922/4885PLA2G4A 4343/4885PLA2G10 3975/4885
US-20170229659-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING THE SAME VDAC2, EED, VDAC3 PLA2G2A 3922/4885PLA2G4A 4343/4885PLA2G10 3975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.