Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.52 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.52 |
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14475593 | 0.90 | MEN1 (0.54) | CYP1A2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL14475886 | 0.76 | MEN1 (0.55) | CYP1A2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL14475231 | 0.75 | MEN1 (0.54) | CYP1A2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL182791 | 0.75 | PIK3CA (0.57) | PIK3CAPIK3CDPIK3CBPIK3CGPIP5K1C | |
| SCHEMBL182718 | 0.74 | PIK3CD (0.61) | CYP1A2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL20280955 | 0.74 | WHR1 (0.71) | CYP1A1CYP1A2CYP1B1ATMPDGFRB | |
| SCHEMBL1422182 | 0.74 | HSD17B1 (0.67) | PIK3CAPIK3CDPIK3CBPIK3CGPIP5K1C | |
| SCHEMBL18023076 | 0.74 | POLB (0.49) | CYP1A2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL2156146 | 0.74 | MEN1 (0.60) | CYP1A2KDM1AMEN1USP2KMT2A | |
| SCHEMBL14474980 | 0.73 | ABCG2 (0.62) | CYP1A1CYP1A2CYP1B1MAP4K4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307477-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | GALENEA CORPORATION | 2015-10-29 | — | — | US | disclosed |
| US-20150307477-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | GALENEA CORPORATION | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307477-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP4C, PTPRG, PPP2CA | CYP1A1 4677/4885CYP1A2 4552/4885CYP1B1 4455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.