Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14475209 | 0.90 | CYP1A2 (0.56) | LMNACYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL17212412 | 0.82 | SYK (0.62) | LMNACYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL14475197 | 0.81 | CYP1A2 (0.62) | LMNACYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL16183479 | 0.78 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19KDM4E | |
| SCHEMBL14474141 | 0.78 | CYP1A2 (0.55) | LMNACYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL18023068 | 0.78 | CYP1A2 (0.55) | LMNACYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL17212414 | 0.77 | SYK (0.66) | LMNACYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL14475884 | 0.76 | CYP1A2 (0.60) | LMNACYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL16183430 | 0.75 | HSD17B10 (0.46) | LMNACYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL17212426 | 0.75 | TRIM58 (0.52) | LMNACYP1A2ALDH1A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307477-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | GALENEA CORPORATION | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307477-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP4C, PTPRG, PPP2CA | LMNA 4848/4885CYP1A2 4552/4885ALDH1A1 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.