Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL2482818 | 0.98 | ALDH1A1 (0.56) | ALDH1A1FKBP5FDPSBLMTDP1 | |
| Pyrophosphoric Acid SCHEMBL17216548 | 0.98 | ALDH1A1 (0.56) | ALDH1A1FKBP5FDPSBLMTDP1 | |
| Pyrophosphoric Acid SCHEMBL8011246 | 0.98 | ALDH1A1 (0.56) | ALDH1A1FKBP5FDPSBLMTDP1 | |
| Pyrophosphoric Acid SCHEMBL17260502 | 0.92 | ALDH1A1 (0.50) | ALDH1A1FKBP5FDPSBLMTDP1 | |
| Triphosphate SCHEMBL22659158 | 0.90 | ALDH1A1 (0.52) | ALDH1A1FKBP5FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL1090914 | 0.89 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Phosphoric Acid SCHEMBL22659156 | 0.89 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Phosphoric Acid SCHEMBL29042477 | 0.89 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Phosphoric Acid SCHEMBL1352614 | 0.89 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Phosphoric Acid SCHEMBL27850773 | 0.89 | ALDH1A1 (0.68) | ALDH1A1FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115011113-A | Flame-retardant material and preparation method thereof | 江苏集萃先进高分子材料研究所有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-111040245-B | Pyropolyphosphoric acid imidazole flame retardant and preparation method thereof | 江苏集萃先进高分子材料研究所有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-111040245-A | Pyropolyphosphoric acid imidazole flame retardant and preparation method thereof | 江苏集萃先进高分子材料研究所有限公司 | 2020-04-21 | — | — | CN | disclosed |