SCHEMBL17218205

SCHEMBL17218205

C=Cc1ccccc1CON=[C]c1cccc(Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 3/20 0.32
IDO1 P14902 2/20 0.32
AGXT P21549 2/20 0.32
MAPT P10636 2/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
KMT2A Q03164 2/20 0.31
HPGD P15428 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
CYP2D6 P10635 1/20 0.31
ALPG P10696 1/20 0.31
HTT P42858 1/20 0.31
MAOB P27338 2/20 0.31
HCRTR1 O43613 1/20 0.30
ALOX12 P18054 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17218202 1.00 ALDH1A1 (0.33) ALDH1A1CYP3A4IDO1AGXTMAPT
SCHEMBL17218124 0.85 ALDH1A1 (0.35) ALDH1A1CYP3A4MAPTCYP1A2CYP2C9
SCHEMBL17218126 0.85 ALDH1A1 (0.35) ALDH1A1CYP3A4MAPTCYP1A2CYP2C9
SCHEMBL17216461 0.85 ALDH1A1 (0.32) ALDH1A1
SCHEMBL17216460 0.85 ALDH1A1 (0.32) ALDH1A1
SCHEMBL17219403 0.85 TP53 (0.34) ALDH1A1MAPTKMT2AHPGDMEN1
SCHEMBL17216678 0.85 MAPT (0.33) MAPT
SCHEMBL17219001 0.85 LMNA (0.32) MAPTKMT2ALMNAMAOBALOX12
SCHEMBL17219003 0.85 LMNA (0.32) MAPTKMT2ALMNAMAOBALOX12
SCHEMBL17215664 0.85 ADRA2C (0.34) KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2940012-B1 TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF SUMITOMO CHEMICAL CO (JP) 2019-01-30 EP disclosed
US-9560850-B2 Tetrazolinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-07 US disclosed
US-20150336908-A1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-26 US disclosed
EP-2940012-A1 TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF Sumitomo Chemical Company Limited (JP) 2015-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336908-A1 TETRAZOLINONE COMPOUND AND USE THEREOF RTN3, CYP51A1, TCOF1 ALDH1A1 2300/4885CYP3A4 266/4885IDO1 2882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.