Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17220417 | 0.85 | P2RX7 (0.41) | HSD11B1MEN1KMT2ACCR6P2RX7 | |
| SCHEMBL4352564 | 0.84 | MEN1 (0.39) | HSD11B1MEN1KMT2APOLBCCR6 | |
| SCHEMBL1535994 | 0.81 | MEN1 (0.37) | HSD11B1MEN1KMT2APOLBCCR6 | |
| SCHEMBL17220053 | 0.80 | MEN1 (0.35) | HSD11B1MEN1KMT2APOLBCCR6 | |
| SCHEMBL17220052 | 0.80 | MEN1 (0.35) | HSD11B1MEN1KMT2APOLBCCR6 | |
| SCHEMBL1536798 | 0.77 | ALDH1A1 (0.40) | HSD11B1MEN1KMT2APOLBCCR6 | |
| SCHEMBL17220562 | 0.74 | L3MBTL1 (0.40) | MEN1KMT2APOLBCCR6EPHX2 | |
| SCHEMBL17220565 | 0.74 | L3MBTL1 (0.40) | MEN1KMT2APOLBCCR6EPHX2 | |
| SCHEMBL1934124 | 0.74 | L3MBTL1 (0.47) | MEN1KMT2APOLBTDP1LMNA | |
| SCHEMBL18855429 | 0.73 | L3MBTL1 (0.46) | MEN1KMT2APOLBTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2299821-B1 | TRICYCLIC COMPOUNDS | ABBVIE INC (US) | 2015-11-04 | — | — | EP | disclosed |