SCHEMBL172223

SCHEMBL172223

C=CC(=O)Oc1cccc(N(c2ccc(OC)cc2)c2cccc(OC(=O)C=C)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 8/20 0.47
MTNR1B P49286 8/20 0.47
HSD17B1 P14061 2/20 0.45
HSD17B2 P37059 2/20 0.45
BCL2A1 Q16548 3/20 0.44
TGM2 P21980 1/20 0.43
THRB P10828 2/20 0.42
TSHR P16473 1/20 0.41
BCHE P06276 2/20 0.40
ACHE P22303 1/20 0.40
SLC16A3 O15427 1/20 0.40
SLC16A1 P53985 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172470 0.99 MTNR1A (0.46) MTNR1AMTNR1BHSD17B1HSD17B2BCL2A1
SCHEMBL9915805 0.91 THRB (0.46) MTNR1AMTNR1BHSD17B1HSD17B2BCL2A1
SCHEMBL11987120 0.91 THRB (0.46) MTNR1AMTNR1BHSD17B1HSD17B2BCL2A1
SCHEMBL12234071 0.89 THRB (0.44) MTNR1AMTNR1BTGM2THRBBCHE
SCHEMBL12234143 0.88 BCHE (0.43) MTNR1AMTNR1BTGM2THRBBCHE
SCHEMBL11987123 0.88 KMT2A (0.41) MTNR1AMTNR1BTGM2THRBBCHE
SCHEMBL172201 0.88 THRB (0.44) MTNR1AMTNR1BHSD17B1HSD17B2TGM2
SCHEMBL13777543 0.87 THRB (0.56) MTNR1AMTNR1BHSD17B1HSD17B2BCL2A1
SCHEMBL12234135 0.87 LMNA (0.41) MTNR1AMTNR1BHSD17B1HSD17B2TGM2
SCHEMBL9915690 0.87 LMNA (0.41) MTNR1AMTNR1BHSD17B1HSD17B2TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
EP-2017676-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2014-07-23 EP disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 US disclosed
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 EP disclosed
US-8043773-B2 surface layer having a good anti-abrasion property, good electric characteristics and a good cleaning property for a spherical toner; photosensitive layer on an electroconductive substrate; Particulates having a needle form are dispersed in the surface layer of the photosensitive layer RICOH COMPANY, LIMITED (JP) 2011-10-25 US disclosed
US-8043773-B2 surface layer having a good anti-abrasion property, good electric characteristics and a good cleaning property for a spherical toner; photosensitive layer on an electroconductive substrate; Particulates having a needle form are dispersed in the surface layer of the photosensitive layer RICOH COMPANY, LIMITED (JP) 2011-10-25 US disclosed
US-7985520-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2011-07-26 US disclosed
US-7985520-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2011-07-26 US disclosed
US-20080318142-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR PREPARING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD AND APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-12-25 US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 US disclosed
US-20080241716-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-10-02 US disclosed
US-20080241716-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-10-02 US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 US disclosed
EP-1847881-A2 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2007-10-24 EP disclosed