SCHEMBL17224656

SCHEMBL17224656

OC(c1cc(F)cc(F)c1)c1c[nH]nc1-c1cc(Cl)cc(Cl)c1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 1/20 0.34
KCND3 Q9UK17 1/20 0.34
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17338372 0.82 CNR2 (0.48) KCNA5KCND3CNR2
SCHEMBL17338447 0.74 CNR2 (0.43) KCNA5KCND3CNR2
SCHEMBL17224635 0.69 CNR1 (0.33) CNR2
SCHEMBL8755909 0.69 MAP4K4 (0.34)
SCHEMBL425389 0.66 TSHR (0.35)
SCHEMBL17224621 0.64 CES2 (0.41)
SCHEMBL8427413 0.63 MAPK13 (0.33) KCNA5
SCHEMBL23340100 0.63 RAB9A (0.31)
SCHEMBL4457007 0.62 CES2 (0.50)
SCHEMBL17224620 0.62 CES2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015167795-A1 HERBICIDAL SUBSTITUTED 3-PHENYL-4-FLUOROBENZOYL PYRAZOLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-11-05 WO disclosed