Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.33 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCND2 | P30279 | 2/20 | 0.33 |
| ▸ | CCND3 | P30281 | 2/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | XPO1 | O14980 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17224658 | 0.90 | CES2 (0.38) | CNR1CNR2CCNB2CCNE2CDK1 | |
| SCHEMBL17224633 | 0.87 | CES2 (0.40) | CNR1CNR2CES2CES1ALDH1A1 | |
| SCHEMBL17224655 | 0.85 | CES2 (0.38) | CES2CES1ALDH1A1HTTNPC1 | |
| SCHEMBL17224621 | 0.83 | CES2 (0.41) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL17338472 | 0.82 | CNR2 (0.49) | CNR1CNR2CCNB2CCNE2CDK1 | |
| SCHEMBL17224620 | 0.81 | CES2 (0.41) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL17224660 | 0.78 | CCNB2 (0.42) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL23294328 | 0.77 | KMO (0.42) | CNR1ALDH1A1RXRARXRBSMN1; SMN2 | |
| SCHEMBL17224662 | 0.75 | CES2 (0.44) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL8182394 | 0.71 | RORB (0.46) | CNR1CNR2CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926278-B2 | Sulfonyl hydrazide compounds and a regio-selective process to prepare 4-aroyl pyrazole derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2018-03-27 | — | — | US | disclosed |
| US-20170044109-A1 | SULFONYL HYDRAZIDE COMPOUNDS AND A REGIO-SELECTIVE PROCESS TO PREPARE 4-AROYL PYRAZOLE DERIVATIVES | FMC CORPORATION | 2017-02-16 | — | — | US | disclosed |
| WO-2015167795-A1 | HERBICIDAL SUBSTITUTED 3-PHENYL-4-FLUOROBENZOYL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044109-A1 | SULFONYL HYDRAZIDE COMPOUNDS AND A REGIO-SELECTIVE PROCESS TO PREPARE 4-AROYL PYRAZOLE DERIVATIVES | ALDH3A1, SQOR, ADORA3 | CNR1 625/4885CNR2 611/4885CCNB2 2904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.