Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | ACR | P10323 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14946881 | 0.89 | PDE4A (0.38) | KDM4EELANEPARP10GLA | |
| SCHEMBL28103046 | 0.81 | MAPK1 (0.47) | KDM4EALDH1A1MAPTMAPK1PARP10 | |
| SCHEMBL14947442 | 0.81 | KMT2A (0.39) | KDM4EELANEALDH1A1MAPTMAPK1 | |
| SCHEMBL28103050 | 0.80 | CA12 (0.52) | KDM4EALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL28097757 | 0.78 | RAB9A (0.47) | ALDH1A1KMT2ALMNACYP2C19 | |
| SCHEMBL28073639 | 0.72 | CA1 (0.53) | ALDH1A1MAPTLMNAPARP10PRSS1 | |
| SCHEMBL27836392 | 0.71 | KDM4E (0.53) | KDM4EMAPTMAPK1MEN1KMT2A | |
| SCHEMBL15495947 | 0.71 | ELANE (0.46) | KDM4EELANEALDH1A1MAPTMAPK1 | |
| SCHEMBL20202282 | 0.70 | HSD17B1 (0.39) | KDM4EELANEALDH1A1MAPTMAPK1 | |
| SCHEMBL28097763 | 0.70 | PARP1 (0.54) | ALDH1A1MEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596082-B1 | POLYMER-STABILIZED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GMBH (DE) | 2015-11-04 | — | — | EP | disclosed |