Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064540 | 0.85 | RAB9A (0.56) | RAB9AALDH1A1THRBSMN1; SMN2LMNA | |
| SCHEMBL4594651 | 0.84 | ELANE (0.56) | RAB9AALDH1A1THRBSMN1; SMN2LMNA | |
| SCHEMBL1835776 | 0.81 | RAB9A (0.53) | RAB9AALDH1A1THRBSMN1; SMN2RXRA | |
| SCHEMBL28073639 | 0.79 | CA1 (0.53) | RAB9AALDH1A1SMN1; SMN2LMNACYP2C19 | |
| SCHEMBL9577400 | 0.79 | RAB9A (0.51) | RAB9AALDH1A1THRBSMN1; SMN2LMNA | |
| SCHEMBL16192677 | 0.79 | ELANE (0.51) | RAB9AALDH1A1THRBSMN1; SMN2RXRA | |
| SCHEMBL17226397 | 0.78 | KDM4E (0.38) | ALDH1A1LMNACYP2C19KMT2A | |
| SCHEMBL8382293 | 0.78 | ALDH1A1 (0.47) | RAB9AALDH1A1THRBSMN1; SMN2LMNA | |
| SCHEMBL28729704 | 0.78 | ALDH1A1 (0.47) | RAB9AALDH1A1THRBSMN1; SMN2LMNA | |
| SCHEMBL7061682 | 0.78 | RAB9A (0.54) | RAB9AALDH1A1THRBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103917094-B | Glucosylceramide Synthase Inhibitors | 建新公司 | 2016-11-09 | — | — | CN | disclosed |