Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24597681 | 0.81 | ESR2 (0.65) | ESR2SLC18A3LIPEALDH1A1PKM | |
| SCHEMBL19937427 | 0.81 | ESR2 (0.65) | ESR2SLC18A3LIPEALDH1A1PKM | |
| SCHEMBL21425138 | 0.78 | ESR2 (0.46) | ESR2SLC18A3LIPEALDH1A1MEN1 | |
| SCHEMBL10454546 | 0.77 | CHRNA7 (0.42) | ALDH1A1PKMMEN1KMT2ALMNA | |
| SCHEMBL17231854 | 0.77 | CHRNA7 (0.42) | ALDH1A1PKMMEN1KMT2ALMNA | |
| SCHEMBL19979366 | 0.76 | RAB9A (0.38) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL17666384 | 0.76 | ESR2 (0.59) | ESR2SLC18A3LIPEALDH1A1PKM | |
| SCHEMBL11280912 | 0.76 | ESR2 (0.59) | ESR2SLC18A3ALDH1A1PKMFFAR1 | |
| SCHEMBL14228683 | 0.76 | ESR2 (0.38) | ESR2 | |
| SCHEMBL14231502 | 0.75 | ESR2 (0.53) | ESR2SLC18A3ALDH1A1PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752075-B2 | Mesogenic media and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-09-05 | — | — | US | disclosed |
| US-20160298031-A1 | MESOGENIC MEDIA AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20160289561-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-10-06 | — | — | US | disclosed |
| US-20160229795-A1 | COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20160222293-A1 | MESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| US-20150315470-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229795-A1 | COMPOUNDS AND MESOGENIC MEDIA | MTX1, NEFM, MTX2 | ESR2 3561/4885SLC18A3 1565/4885LIPE 1553/4885 |
| US-20160289561-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | SP1, FOXM1, S100A11 | ESR2 1263/4885SLC18A3 3748/4885LIPE 4429/4885 |
| US-20150315470-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | SP1, FOXM1, S100A11 | ESR2 1738/4885SLC18A3 3991/4885LIPE 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.