Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 11/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYBB | P04839 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844654 | 0.87 | NOX4 (0.50) | NOX4CYBBCYP3A4NOX1 | |
| SCHEMBL1723241 | 0.67 | NOX4 (0.53) | NOX4CYBBCYP3A4NOX1 | |
| SCHEMBL2846433 | 0.67 | NOX4 (0.56) | NOX4CYBBCYP3A4NOX1 | |
| SCHEMBL1302005 | 0.66 | NOX4 (0.56) | NOX4CYBBCYP3A4NOX1 | |
| SCHEMBL6763210 | 0.65 | PRKX (0.58) | NOX4NOTUMALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1302490 | 0.62 | NOX4 (0.55) | NOX4CYBBCYP3A4NOX1 | |
| SCHEMBL7577911 | 0.62 | NOTUM (0.43) | NOTUMHTTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7070074 | 0.62 | ALDH1A1 (0.69) | NOX4NOTUMHTTALDH1A1KDM4E | |
| SCHEMBL10995515 | 0.61 | ALDH1A1 (0.41) | NOTUMHTTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL27756001 | 0.61 | DAO (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344492-A1 | PYRAZOLO PYRIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GenKyoTex SA (CH) | 2011-07-20 | — | — | EP | disclosed |