Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722406 | 0.90 | LMNA (0.58) | LMNAHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL321271 | 0.90 | LMNA (0.45) | LMNAHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1725046 | 0.89 | LMNA (0.54) | LMNAHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL302104 | 0.86 | LMNA (0.61) | LMNAHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1723243 | 0.86 | LMNA (0.54) | LMNAHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL303115 | 0.84 | LMNA (0.52) | LMNAHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL303692 | 0.84 | LMNA (0.66) | LMNAHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1711049 | 0.83 | LMNA (0.62) | LMNAHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL302045 | 0.80 | SLC6A7 (0.53) | LMNAHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL306227 | 0.80 | TSHR (0.49) | LMNAHTTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344456-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | Xention Limited (GB) | 2011-07-20 | — | — | EP | disclosed |