SCHEMBL1723906

SCHEMBL1723906

CCCCCc1ccc2[nH]c3ccccc3c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 3/20 0.56
GABRD O14764 3/20 0.56
GABRA1 P14867 3/20 0.56
GABRB1 P18505 3/20 0.56
GABRG2 P18507 3/20 0.56
GABRB3 P28472 3/20 0.56
GABRA5 P31644 3/20 0.56
GABRA3 P34903 3/20 0.56
GABRA2 P47869 3/20 0.56
GABRB2 P47870 3/20 0.56
GABRA4 P48169 3/20 0.56
GABRE P78334 3/20 0.56
GABRA6 Q16445 3/20 0.56
GABRG1 Q8N1C3 3/20 0.56
GABRG3 Q99928 3/20 0.56
GABRQ Q9UN88 3/20 0.56
IDO1 P14902 1/20 0.56
CTSV O60911 3/20 0.56
CTSL P07711 3/20 0.56
KIF11 P52732 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31522705 1.00 GABRP (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17779615 0.98 CTSV (0.58) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9163470 0.98 CTSV (0.58) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL31522707 0.95 GABRP (0.61) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL31522704 0.95 GABRP (0.61) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL4062550 0.95 GABRP (0.61) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL532789 0.92 HTR1A (0.55) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11296266 0.90 KIF11 (0.68) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1128166 0.90 HTR1A (0.57) CTSVCTSLHTR1AHTR1DHTR1B
SCHEMBL12795553 0.90 HTR1A (0.57) CTSVCTSLHTR1AHTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140187791-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-03 US disclosed
US-8669373-B2 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-11 US disclosed
EP-2330097-B1 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LAB (JP) 2013-01-23 EP disclosed
EP-2166001-B1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LAB (JP) 2011-07-20 EP disclosed
EP-2330097-A1 Carbazole derivative and method for producing the same Semiconductor Energy Laboratory Co, Ltd. (JP) 2011-06-08 EP disclosed
US-20100076201-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-25 US disclosed
EP-2166001-A1 Carbazole Derivative and Method for Producing the Same Semiconductor Energy Laboratory Co., Ltd. (JP) 2010-03-24 EP disclosed
CN-101676265-A Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LAB 2010-03-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076201-A1 Carbazole Derivative and Method for Producing the Same AADAC, CYP1A1, CYP1B1 GABRP 2659/4885GABRD 1105/4885GABRA1 847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.