Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17239095 | 0.77 | ATM (0.36) | TSHRLMNACES1CES2MAPK1 | |
| SCHEMBL17239117 | 0.77 | TDP1 (0.35) | TSHRLMNAHTTMEN1KMT2A | |
| SCHEMBL4966849 | 0.76 | TSHR (0.44) | TSHRLMNACES1CES2MAPK1 | |
| SCHEMBL28728329 | 0.76 | TSHR (0.44) | TSHRLMNACES1CES2MAPK1 | |
| SCHEMBL8401904 | 0.75 | CES2 (0.39) | TSHRCES1CES2MAPK1L3MBTL1 | |
| SCHEMBL18411740 | 0.74 | TSHR (0.43) | TSHRLMNACES1CES2MAPK1 | |
| SCHEMBL1433790 | 0.74 | TSHR (0.43) | TSHRLMNACES1CES2MAPK1 | |
| SCHEMBL14956511 | 0.74 | LMNA (0.46) | LMNACES1CES2L3MBTL1MEN1 | |
| SCHEMBL5165599 | 0.73 | TSHR (0.46) | TSHRLMNACES1CES2MAPK1 | |
| SCHEMBL24089157 | 0.70 | HDAC1 (0.50) | TSHRLMNAMAPK1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512272-B2 | Curable composition containing silicone, and cured product thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20150322211-A1 | Curable Composition Containing Silicone, and Cured Product Thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2015-11-12 | — | — | US | disclosed |