Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17239063 | 0.77 | TSHR (0.41) | TDP1LMNATSHRMAPTNPC1 | |
| SCHEMBL17239095 | 0.72 | ATM (0.36) | SMN1; SMN2LMNATSHRMAPTNPC1 | |
| SCHEMBL8401904 | 0.71 | CES2 (0.39) | TDP1TSHRMAPTALDH1A1ATM | |
| SCHEMBL14956511 | 0.69 | LMNA (0.46) | TDP1KDM4ESMN1; SMN2LMNAMAPT | |
| Benzil SCHEMBL28397664 | 0.67 | CES2 (0.54) | TDP1KDM4EPDCD1CD274SMN1; SMN2 | |
| SCHEMBL2270556 | 0.64 | ALDH1A1 (0.38) | TDP1KDM4ESMN1; SMN2TSHRMAPT | |
| SCHEMBL662843 | 0.64 | LMNA (0.36) | KDM4ESMN1; SMN2LMNATSHRMAPT | |
| SCHEMBL23045159 | 0.64 | ESR1 (0.35) | TDP1SMN1; SMN2LMNATSHRMAPT | |
| SCHEMBL2267686 | 0.64 | RECQL (0.44) | KDM4ELMNAMAPTNPC1RAB9A | |
| SCHEMBL2270399 | 0.64 | TSHR (0.39) | TDP1KDM4ESMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512272-B2 | Curable composition containing silicone, and cured product thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20150322211-A1 | Curable Composition Containing Silicone, and Cured Product Thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2015-11-12 | — | — | US | disclosed |