SCHEMBL1723977

SCHEMBL1723977

ONc1cccc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3123627 0.81 IDO1 (0.61)
SCHEMBL8795345 0.79 MAPT (0.61)
SCHEMBL1686631 0.79 FADS1 (0.59)
SCHEMBL24173759 0.79 HTR3E (0.56)
SCHEMBL5158903 0.77
SCHEMBL3202726 0.75
SCHEMBL21835149 0.75
SCHEMBL24300038 0.75
SCHEMBL357405 0.75
SCHEMBL19334340 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105399666-A Fungicide hydroxyimino-heterocyclic derivatives BAYER CROSPSCIENCE AG 2016-03-16 CN claimed
CN-102725270-A Fungicide hydroxyimino-heterocyclic derivatives BAYER CROPSCIENCE AG 2012-10-10 CN claimed
CN-112774670-A Application of rhodium monatomic catalyst in reaction for preparing m-chloroaniline through selective hydrogenation of m-chloronitrobenzene 中国科学院大连化学物理研究所 2021-05-11 CN disclosed
US-20210000799-A1 CHEMICAL INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS DOSRST SIGNALING AND PERSISTENCE BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2021-01-07 US disclosed
US-20160115139-A1 PROCESS FOR MAKING BENZOXAZINES CYTEC INDUSTRIES INC. (US) 2016-04-28 US disclosed
US-20160115139-A1 PROCESS FOR MAKING BENZOXAZINES CYTEC INDUSTRIES INC. (US) 2016-04-28 US disclosed
CN-105399666-A Fungicide hydroxyimino-heterocyclic derivatives BAYER CROSPSCIENCE AG 2016-03-16 CN disclosed
CN-102725270-B Fungicide hydroxyimino-heterocyclic derivatives BAYER CROPSCIENCE AG (DE) 2015-10-07 CN disclosed
US-8816095-B2 Na channels, disease, and related assays and compositions GEORGETOWN UNIVERSITY (US) 2014-08-26 US disclosed
CN-102725270-A Fungicide hydroxyimino-heterocyclic derivatives BAYER CROPSCIENCE AG 2012-10-10 CN disclosed
EP-2368891-B1 Pyrimidines derivatives as antagonists of the vitronectine receptors GALAPAGOS NV (BE) 2012-09-19 EP disclosed
EP-2343974-A2 NA CHANNELS, DISEASE, AND RELATED ASSAYS AND COMPOSITIONS Georgetown University (US) 2011-07-20 EP disclosed
WO-2010027641-A2 NA CHANNELS, DISEASE, AND RELATED ASSAYS AND COMPOSITIONS GEORGETOWN UNIVERSITY (US) 2010-03-11 WO disclosed
WO-2010019963-A2 NA CHANNELS, DISEASE, AND RELATED ASSAYS AND COMPOSITIONS GEORGETOWN UNIVERSITY (US) 2010-02-18 WO disclosed
EP-0373216-A1 CEPHALOSPORIN COMPOUNDS OR THEIR SALTS, PROCESS FOR THEIR PREPARATION, AND PARMACEUTICAL COMPOSITIONS TEIJIN LIMITED (JP) 1990-06-20 EP disclosed
US-4224340-A Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds WILLIAM H. RORER, INC. (US) 1980-09-23 US disclosed
US-4214003-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1980-07-22 US disclosed
US-4197314-A WITH A DIPHENYL NITRONE WILLIAM H. RORER, INC. (US) 1980-04-08 US disclosed
US-4153722-A ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE WILLIAM H. RORER, INC. (US) 1979-05-08 US disclosed
US-3982922-A Herbicidal compositions containing furancarboxamides VELSICOL CHEMICAL CORPORATION (US) 1976-09-28 US disclosed