⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Chloroaniline SCHEMBL28001348 | 0.87 | ALDH1A1 (0.68) | — | |
| SCHEMBL1686631 | 0.81 | FADS1 (0.59) | — | |
| SCHEMBL8795345 | 0.81 | MAPT (0.61) | — | |
| SCHEMBL2481143 | 0.80 | MAPT (0.55) | — | |
| SCHEMBL24300038 | 0.77 | — | — | |
| SCHEMBL3202726 | 0.77 | — | — | |
| SCHEMBL1723977 | 0.77 | — | — | |
| SCHEMBL21835149 | 0.77 | — | — | |
| SCHEMBL103824 | 0.77 | — | — | |
| SCHEMBL357405 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4532350-A | Process for the selective preparation of meta-chloroanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-07-30 | — | — | US | claimed |
| EP-0086726-B1 | PROCESS FOR THE PREPARATION OF META-HALOGEN-ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1985-06-26 | — | — | EP | claimed |
| US-4495368-A | Process for the preparation of meta-halogenoanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-01-22 | — | — | US | claimed |
| EP-0045709-B1 | PROCESS FOR THE PREPARATION OF META-CHLORINATED ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1984-10-03 | — | — | EP | claimed |
| EP-0045710-B1 | PROCESS FOR THE SELECTIVE PREPARATION OF META-CHLORINATED ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1984-07-04 | — | — | EP | claimed |
| US-4418213-A | HYDRODEHALOGENATION LEWIS ACID AND NOBLE METAL CATALYSTS | RHONE-POULENC AGROCHIMIE (FR) | 1983-11-29 | — | — | US | claimed |
| US-4351959-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-09-28 | — | — | US | claimed |
| US-4340759-A | Process for the preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-07-20 | — | — | US | claimed |
| EP-0015220-B1 | PROCESS FOR THE PREPARATION OF META-CHLORO ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1982-05-12 | — | — | EP | claimed |
| US-4324914-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-04-13 | — | — | US | claimed |
| EP-0015219-B1 | PROCESS FOR THE PREPARATION OF META-CHLORO ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1981-10-28 | — | — | EP | claimed |
| EP-0021598-A1 | A kinetic method for directly determining total bilirubin | BECKMAN INSTRUMENTS, INC. (US) | 1981-01-07 | — | — | EP | claimed |
| CN-118027070-A | Triazolopyridine bromodomain protein 4 small molecule inhibitor and preparation method and application thereof | 中国药科大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-110407665-B | Chlorinated aromatic compound (R)1-Xm) Dechlorination method of | 厦门大学 | 2021-01-26 | — | — | CN | disclosed |
| CN-110407665-A | A kind of chlorinated aromatic compound (R1-Xm) dechlorination method | UNIV XIAMEN | 2019-11-05 | — | — | CN | disclosed |
| CN-106068262-B | Quinazoline derivant and preparation method thereof and application in medicine | HAISCO PHARMACEUTICAL GROUP INC. (CN) | 2019-10-29 | — | — | CN | disclosed |
| US-4353734-A | PRE- AND POSTEMERGENCE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1982-10-12 | — | — | US | disclosed |
| US-4311483-A | Kinetic method for directly determining total bilirubin | BECKMAN INSTRUMENTS, INC. (US) | 1982-01-19 | — | — | US | disclosed |
| EP-0021598-A1 | A kinetic method for directly determining total bilirubin | BECKMAN INSTRUMENTS, INC. (US) | 1981-01-07 | — | — | EP | disclosed |
| US-3936556-A | Marking of articles | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | disclosed |