Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.41 |
| ▸ | DUT | P33316 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18622522 | 0.93 | HCAR2 (0.53) | ATMHCAR2DUTMAPTRAB9A | |
| SCHEMBL17242155 | 0.87 | DUT (0.37) | ATMDUTALDH1A1TP53TSHR | |
| SCHEMBL13028473 | 0.85 | TSHR (0.52) | DUTALDH1A1TP53TSHRHIF1A | |
| SCHEMBL6577144 | 0.81 | DUT (0.34) | DUTTHRB | |
| SCHEMBL23461816 | 0.78 | LMNA (0.41) | DUTTSHRHSD17B10 | |
| SCHEMBL7201380 | 0.78 | DUT (0.36) | DUT | |
| SCHEMBL29603998 | 0.77 | NAAA (0.42) | DUTALDH1A1HIF1A | |
| SCHEMBL28519906 | 0.77 | DUT (0.41) | DUTALDH1A1TP53TSHRHIF1A | |
| SCHEMBL28519902 | 0.77 | DUT (0.41) | DUTALDH1A1TP53TSHRHIF1A | |
| SCHEMBL5702812 | 0.76 | MAPT (0.49) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073452-A1 | POLYGLYOXYLATES, MANUFACTURE AND USE THEREOF | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2017-03-16 | — | — | US | disclosed |
| WO-2015168809-A1 | POLYGLYOXYLATES, MANUFACTURE AND USE THEREOF | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2015-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073452-A1 | POLYGLYOXYLATES, MANUFACTURE AND USE THEREOF | IDUA, IDE, PUF60 | ATM 3431/4885HCAR2 1437/4885DUT 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.