Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | CCR1 | P32246 | 4/20 | 0.54 |
| ▸ | CCR5 | P51681 | 4/20 | 0.54 |
| ▸ | CCR8 | P51685 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.47 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399098 | 0.88 | CCR1 (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL11996115 | 0.85 | CCR1 (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL19039501 | 0.82 | KDM4E (0.47) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL12386860 | 0.82 | KDM4E (0.47) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL14054103 | 0.81 | ASIC3 (0.53) | KDM4ELMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL23914094 | 0.80 | KDM4E (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL19362627 | 0.80 | CCR1 (0.41) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL7679401 | 0.80 | CCR1 (0.41) | KDM4ELMNACCR1CCR5CCR8 | |
| Hydrochloric Acid SCHEMBL28148517 | 0.79 | ASIC3 (0.52) | KDM4ELMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL9261215 | 0.78 | CTSK (0.50) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759994-B2 | Luminogenic transition metal-based pyridyl complex and its use | CITY UNIVERSITY OF HONG KONG (HK) | 2020-09-01 | — | — | US | disclosed |
| US-20180142144-A1 | LUMINOGENIC TRANSITION METAL-BASED PYRIDYL COMPLEX AND ITS USE | CITY UNIVERSITY OF HONG KONG (HK) | 2018-05-24 | — | — | US | disclosed |
| US-9181204-B2 | Chemical compounds capable of complexing at least one metal element and a coordination complex based on these compounds | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759994-B2 | Luminogenic transition metal-based pyridyl complex and its use | TK1, NOX5, PDXK | KDM4E 3901/4885LMNA 1746/4885CCR1 3738/4885 |
| US-20180142144-A1 | LUMINOGENIC TRANSITION METAL-BASED PYRIDYL COMPLEX AND ITS USE | TK1, NOX5, PDXK | KDM4E 3901/4885LMNA 1746/4885CCR1 3738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.