Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17040266 | 0.89 | APLNR (0.40) | S1PR1FPR2BCHEACHEHDAC1 | |
| SCHEMBL17040094 | 0.87 | HDAC1 (0.46) | S1PR1PTPN11HDAC1HDAC8HDAC6 | |
| SCHEMBL19066438 | 0.84 | KMO (0.41) | S1PR1HDAC1HDAC8HDAC6PTPN1 | |
| SCHEMBL30484467 | 0.84 | KMO (0.41) | S1PR1HDAC1HDAC8HDAC6PTPN1 | |
| SCHEMBL17243833 | 0.83 | PTPN1 (0.44) | PTPN1XDH | |
| SCHEMBL17040267 | 0.83 | IL6 (0.42) | S1PR1FPR2BCHEACHEESR1 | |
| SCHEMBL15521534 | 0.81 | BCHE (0.39) | S1PR1FPR2BCHEACHEESR1 | |
| SCHEMBL4284422 | 0.80 | S1PR1 (0.61) | S1PR1 | |
| SCHEMBL17037222 | 0.78 | DHODH (0.42) | S1PR1HDAC1HDAC8HDAC6XDH | |
| SCHEMBL17037232 | 0.78 | CA9 (0.42) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181205-B2 | Method for producing oxazole compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |