Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | HTR1B | P28222 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.42 |
| ▸ | WNT3A | P56704 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827503 | 0.94 | CYP2A6 (0.42) | CYP2A6CYP1A2HTR1BKDM4ECYP3A4 | |
| SCHEMBL21500400 | 0.83 | CA2 (0.49) | CYP2A6HTR1BKDM4ECYP3A4CYP2D6 | |
| Morpholine SCHEMBL28247332 | 0.82 | APEX1 (0.40) | CYP2A6CYP1A2HTR1BKDM4ECYP3A4 | |
| SCHEMBL30455978 | 0.81 | CTNNB1 (0.54) | CYP2A6CYP1A2HTR1BCTNNB1WNT3A | |
| SCHEMBL172397 | 0.81 | CTNNB1 (0.54) | CYP2A6CYP1A2HTR1BCTNNB1WNT3A | |
| SCHEMBL18574533 | 0.79 | PIN1 (0.41) | CYP1A2HTR1BKDM4ECYP3A4CYP2D6 | |
| SCHEMBL29078438 | 0.78 | EGFR (0.45) | CYP2A6CYP1A2HTR1BKDM4ECYP3A4 | |
| Benzene SCHEMBL28069373 | 0.77 | MAOB (0.52) | CYP2A6CYP1A2HTR1BKDM4ECTNNB1 | |
| SCHEMBL29756248 | 0.75 | DYRK1A (0.50) | CYP2A6HTR1BKDM4ECYP3A4CYP2D6 | |
| SCHEMBL21240994 | 0.74 | CCR1 (0.50) | CYP2A6HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 671 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484467-A | Preparation method of sitagliptin intermediate | 雅本化学股份有限公司 | 2020-08-04 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| EP-3082884-B1 | AIR CARE AND CLEANING PRODUCTS CONTAINING CNGA2 ANTAGONISTS | HENKEL AG & CO KGAA (DE) | 2018-02-28 | — | — | EP | claimed |
| EP-3083910-B1 | USE OF CNGA2 AGONISTS FOR ENHANCING THE OLFACTORY EFFECT OF AN ODORANT | HENKEL AG & CO KGAA (DE) | 2017-09-06 | — | — | EP | claimed |
| EP-3083910-A1 | USE OF CNGA2 AGONISTS FOR ENHANCING THE OLFACTORY EFFECT OF AN ODORANT | Henkel AG & Co. KGaA (DE) | 2016-10-26 | — | — | EP | claimed |
| EP-3082884-A1 | AIR CARE AND CLEANING PRODUCTS CONTAINING CNGA2 ANTAGONISTS | Henkel AG & Co. KGaA (DE) | 2016-10-26 | — | — | EP | claimed |
| US-20160289594-A1 | USE OF CNGA2 AGONISTS FOR ENHANCING THE OLFACTORY EFFECT OF AN ODORANT | HENKEL AG & CO. KGAA (DE) | 2016-10-06 | — | — | US | claimed |
| WO-2015091056-A1 | USE OF CNGA2 AGONISTS FOR ENHANCING THE OLFACTORY EFFECT OF AN ODORANT | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | WO | claimed |
| WO-2015091055-A1 | AIR CARE AND CLEANING PRODUCTS CONTAINING CNGA2 ANTAGONISTS | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | WO | claimed |
| US-8053457-B2 | 3-imidazolyl-indoles for the treatment of proliferative diseases | NOVARTIS AG (CH) | 2011-11-08 | — | — | US | claimed |
| US-20100125064-A1 | 3-Imidazolyl-Indoles for the Treatment of Proliferative Diseases | NOVARTIS AG (CH) | 2010-05-20 | — | — | US | claimed |
| EP-2142535-A2 | 3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis Ag (CH) | 2010-01-13 | — | — | EP | claimed |
| WO-2008119741-A2 | 3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2008-10-09 | — | — | WO | claimed |
| EP-3860994-B1 | TRANSCRIPTION FACTOR BRN2 INHIBITORY COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | UNIV BRITISH COLUMBIA (CA) | 2024-08-14 | — | — | EP | disclosed |
| US-20240239754-A1 | PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20240239754-A1 | PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) | 2024-07-18 | — | — | US | disclosed |
| EP-0132130-A2 | Aroyl benzofuran and benzothiophene acetic and propionic acids processes for their production and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-23 | — | — | EP | disclosed |
| US-4372970-A | NONPHYTOTOXIC, PHOTOSTABLE | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1983-02-08 | — | — | US | disclosed |
| WO-1981001408-A1 | SUBSTITUTED ACETIC ACID ESTERS AS PESTICIDES | SOREX LTD (GB) | 1981-05-28 | — | — | WO | disclosed |
| EP-0029360-A1 | Pesticidal compounds, compositions containing them and methods of killing arthropods using them | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239754-A1 | PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | PAH, HTR3D, CYP3A4 | CYP2A6 299/4885CYP1A2 44/4885HTR1B 1203/4885 |
| US-20160289594-A1 | USE OF CNGA2 AGONISTS FOR ENHANCING THE OLFACTORY EFFECT OF AN ODORANT | CNR2, OR51E2, CHRNA2 | CYP2A6 2607/4885CYP1A2 2156/4885HTR1B 344/4885 |
| US-20100125064-A1 | 3-Imidazolyl-Indoles for the Treatment of Proliferative Diseases | MDM4, TP53, MDM2 | CYP2A6 2778/4885CYP1A2 1527/4885HTR1B 1770/4885 |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | CYP2A6 2194/4885CYP1A2 2553/4885HTR1B 4496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.