Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 3/20 | 0.35 |
| ▸ | ARG2 | P78540 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 10/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137919 | 0.89 | ARG1 (0.38) | TDP1ARG1ARG2AKT1 | |
| SCHEMBL8667941 | 0.85 | ALOX5 (0.36) | ARG1ARG2AKT1 | |
| SCHEMBL14697385 | 0.85 | ALOX5 (0.36) | ARG1ARG2AKT1 | |
| SCHEMBL16653037 | 0.85 | ALOX5 (0.36) | ARG1ARG2AKT1 | |
| SCHEMBL16652985 | 0.85 | ALOX5 (0.36) | ARG1ARG2AKT1 | |
| SCHEMBL8411260 | 0.85 | ALOX5 (0.36) | ARG1ARG2AKT1 | |
| SCHEMBL20856928 | 0.84 | TDP1 (0.38) | TDP1ARG1ARG2 | |
| SCHEMBL2444946 | 0.83 | ARG1 (0.37) | ARG1ARG2AKT1 | |
| Ammonia Solution, Strong SCHEMBL7720467 | 0.82 | CYP1A2 (0.37) | TDP1ARG1ARG2 | |
| SCHEMBL11627387 | 0.80 | ALOX15 (0.39) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402300-B1 | Hydroxyl compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS INC (US) | 2016-05-25 | — | — | EP | disclosed |
| EP-2404890-A1 | Hydroxyl compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2012-01-11 | — | — | EP | disclosed |