Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 3/20 | 0.37 |
| ▸ | ARG2 | P78540 | 2/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.36 |
| ▸ | AKT1 | P31749 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137919 | 0.93 | ARG1 (0.38) | ARG1ARG2AKT1 | |
| SCHEMBL8411260 | 0.89 | ALOX5 (0.36) | ARG1ARG2AKT1 | |
| SCHEMBL8667941 | 0.89 | ALOX5 (0.36) | ARG1ARG2AKT1 | |
| SCHEMBL14697385 | 0.89 | ALOX5 (0.36) | ARG1ARG2AKT1 | |
| SCHEMBL16652985 | 0.89 | ALOX5 (0.36) | ARG1ARG2AKT1 | |
| SCHEMBL16653037 | 0.89 | ALOX5 (0.36) | ARG1ARG2AKT1 | |
| SCHEMBL9514241 | 0.88 | ARG1 (0.34) | ARG1ARG2 | |
| SCHEMBL11627387 | 0.86 | ALOX15 (0.39) | ARG1ARG2 | |
| SCHEMBL1724499 | 0.83 | TDP1 (0.37) | ARG1ARG2AKT1 | |
| SCHEMBL14697190 | 0.82 | NAAA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53046969-A | — | — | None | — | — | JP | disclosed |
| JP-53046970-A | — | — | None | — | — | JP | disclosed |
| JP-52091856-A | — | — | None | — | — | JP | disclosed |
| JP-51128961-A | — | — | None | — | — | JP | disclosed |
| JP-51128962-A | — | — | None | — | — | JP | disclosed |
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-8026273-B2 | 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-27 | — | — | US | disclosed |
| US-20100113388-A1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
| US-7683094-B2 | 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-23 | — | — | US | disclosed |
| US-20090042885-A1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| US-7402605-B2 | 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-07-22 | — | — | US | disclosed |
| US-20050124577-A1 | 8-Azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-09 | — | — | US | disclosed |
| EP-1481976-A1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-4113873-A | 8-AZAPROSTANOIC ACID DERIVATIVES | TANABE SEIYAKU CO. LTD. (JP) | 1978-09-12 | — | — | US | disclosed |
| US-4113873-A | 8-AZAPROSTANOIC ACID DERIVATIVES | TANABE SEIYAKU CO. LTD. (JP) | 1978-09-12 | — | — | US | disclosed |
| JP-S5346970-A | 8-AZAPROSTANOIC ACIDS AND THEIR PREPARATION | TANABE SEIYAKU CO LTD | 1978-04-27 | — | — | JP | disclosed |
| JP-S5346969-A | 8-AZAPROSTANOIC ACIDS AND THEIR PREPARATION | TANABE SEIYAKU CO LTD | 1978-04-27 | — | — | JP | disclosed |
| JP-S5291856-A | 2-PYRROLIDONE DERIVATIVES | TANABE SEIYAKU CO LTD | 1977-08-02 | — | — | JP | disclosed |
| JP-S51128962-A | PROCESS FOR PREPARING 8-AZAPROSTANOIC ACID DERIVATIVES | TANABE SEIYAKU CO LTD | 1976-11-10 | — | — | JP | disclosed |
| JP-S51128961-A | PROCESS FOR PREPARING 8-AZAPROSTANOIC ACID DERIVATIVES | TANABE SEIYAKU CO LTD | 1976-11-10 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124577-A1 | 8-Azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient | PTGER2, PTGIS, HPGDS | ARG1 1924/4885ARG2 850/4885CPB2 442/4885 |
| US-20090042885-A1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT | PTGER2, PTGIS, HPGDS | ARG1 2268/4885ARG2 1291/4885CPB2 410/4885 |
| US-20100113388-A1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT | PTGER2, PTGIS, HPGDS | ARG1 2268/4885ARG2 1291/4885CPB2 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.