Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18403246 | 1.00 | KMT2A (0.36) | KMT2AL3MBTL1SCN9AGAACTSS | |
| SCHEMBL17245242 | 0.87 | KMT2A (0.41) | KMT2AL3MBTL1SCN9A | |
| SCHEMBL17245235 | 0.87 | KMT2A (0.34) | KMT2AL3MBTL1SCN9AGAA | |
| SCHEMBL16864922 | 0.87 | GAA (0.39) | SCN9AGAACTSSCTSK | |
| SCHEMBL16865265 | 0.86 | SCN9A (0.33) | KMT2AL3MBTL1SCN9AGAA | |
| SCHEMBL16865270 | 0.86 | SCN9A (0.35) | KMT2AL3MBTL1SCN9AGAA | |
| SCHEMBL16865313 | 0.86 | SCN9A (0.33) | KMT2AL3MBTL1SCN9AGAA | |
| SCHEMBL17245232 | 0.86 | CCR2 (0.35) | SCN9A | |
| SCHEMBL16865251 | 0.84 | KMT2A (0.39) | KMT2AL3MBTL1 | |
| SCHEMBL16865259 | 0.84 | OPRK1 (0.33) | KMT2AL3MBTL1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9549555-B2 | Macrocyclic picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-9549555-B2 | Macrocyclic picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-9247741-B2 | Use of macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2016-02-02 | — | — | US | disclosed |
| US-9247741-B2 | Use of macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150181867-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-07-02 | — | — | US | disclosed |
| US-20150181867-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-07-02 | — | — | US | disclosed |
| US-20150183759-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC | 2015-07-02 | — | — | US | disclosed |
| WO-2015100182-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183759-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CYP51A1, PFAS, AADAC | KMT2A 2871/4885L3MBTL1 4494/4885SCN9A 956/4885 |
| US-20150181867-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | FKBP14, CYP4F12, CYP1A2 | KMT2A 3287/4885L3MBTL1 4382/4885SCN9A 1389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.