Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | PPARA | Q07869 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10417536 | 1.00 | MMP1 (0.43) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL17245264 | 1.00 | MMP1 (0.43) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL1195466 | 0.87 | SLC1A3 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL1196065 | 0.87 | SLC1A3 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL6675517 | 0.87 | SLC1A3 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL24067986 | 0.76 | ALDH1A1 (0.38) | SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL12057009 | 0.76 | SMN1; SMN2 (0.43) | CA1CA2CA7 | |
| SCHEMBL10591979 | 0.75 | SLC1A3 (0.45) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9353746 | 0.75 | TSHR (0.37) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL10434366 | 0.74 | MAPK1 (0.34) | MMP1MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150320753-A1 | PURINE DERIVATIVE COMPOUNDS FOR MEDICAL USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-12 | — | — | US | disclosed |
| US-20150320753-A1 | PURINE DERIVATIVE COMPOUNDS FOR MEDICAL USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320753-A1 | PURINE DERIVATIVE COMPOUNDS FOR MEDICAL USE | MSR1, TPMT, M6PR | MMP1 2676/4885MMP2 2735/4885MMP3 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.