Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675517 | 1.00 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1ALDH1A1MAPT | |
| SCHEMBL1195466 | 1.00 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1ALDH1A1MAPT | |
| SCHEMBL17245264 | 0.87 | MMP1 (0.43) | SLC1A3SLC1A2SLC1A1ALDH1A1MAPT | |
| SCHEMBL10417536 | 0.87 | MMP1 (0.43) | SLC1A3SLC1A2SLC1A1ALDH1A1MAPT | |
| SCHEMBL17245265 | 0.87 | MMP1 (0.43) | SLC1A3SLC1A2SLC1A1ALDH1A1MAPT | |
| SCHEMBL9353746 | 0.86 | TSHR (0.37) | SLC1A3SLC1A2SLC1A1TP53TSHR | |
| SCHEMBL24067986 | 0.83 | ALDH1A1 (0.38) | SLC1A3SLC1A2SLC1A1ALDH1A1TSHR | |
| SCHEMBL27868667 | 0.78 | — | — | |
| SCHEMBL13484732 | 0.77 | ALDH1A1 (0.35) | ALDH1A1MAPTPTGS1TP53TSHR | |
| SCHEMBL17416331 | 0.76 | ADH1B (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759583-B2 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | TEVA SANTE (FR) | 2014-06-24 | — | — | US | disclosed |
| US-20130066111-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Modafinil by Asymmetric Oxidation | CEPHALON FRANCE (FR) | 2013-03-14 | — | — | US | disclosed |
| US-8318979-B2 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CEPHALON FRANCE (FR) | 2012-11-27 | — | — | US | disclosed |
| EP-1863760-B1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF THIO-SUBSTITUTED ARYLMETHANESULFINYL DERIVATIVES BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2012-10-03 | — | — | EP | disclosed |
| US-8183294-B2 | Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation | Cephelon France (FR) | 2012-05-22 | — | — | US | disclosed |
| US-20120123161-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Modafinil by Asymmetric Oxidation | CEPHALON FRANCE (FR) | 2012-05-17 | — | — | US | disclosed |
| US-20110098505-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Thio-Substituted Arylmethanesulfinyl Derivatives by Asymmetric Oxidation | CEPHALON FRANCE (FR) | 2011-04-28 | — | — | US | disclosed |
| US-7915449-B2 | Contacting the corresponding sulfur compound with complex, bas and oxidizer; oxidation; isolation | CEPHALON FRANCE (FR) | 2011-03-29 | — | — | US | disclosed |
| US-7893111-B2 | Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation | CEPHALON FRANCE (FR) | 2011-02-22 | — | — | US | disclosed |
| CN-101977909-A | Dexlansoprazole process and polymorphs | REDDYS LAB LTD DR | 2011-02-16 | — | — | CN | disclosed |
| US-7317126-B2 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CEPHALON FRANCE (FR) | 2008-01-08 | — | — | US | disclosed |
| EP-1863760-A1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF THIO-SUBSTITUTED ARYLMETHANESULFINYL DERIVATIVES BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2007-12-12 | — | — | EP | disclosed |
| EP-1663963-B1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF MODAFINIL BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006097814-A1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF THIO-SUBSTITUTED ARYLMETHANESULFINYL DERIVATIVES BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2006-09-21 | — | — | WO | disclosed |
| EP-1702915-A1 | Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation | CEPHALON FRANCE (FR) | 2006-09-20 | — | — | EP | disclosed |
| US-20060205706-A1 | Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation | CEPHALON FRANCE (FR) | 2006-09-14 | — | — | US | disclosed |
| EP-1663963-A1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF MODAFINIL BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2006-06-07 | — | — | EP | disclosed |
| US-20050222257-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CEPHALON, INC. (US) | 2005-10-06 | — | — | US | disclosed |
| US-20050080256-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | TEVA SANTE (FR) | 2005-04-14 | — | — | US | disclosed |
| WO-2005028428-A1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF MODAFINIL BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098505-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Thio-Substituted Arylmethanesulfinyl Derivatives by Asymmetric Oxidation | SULT1A1, TST, SULT2A1 | SLC1A3 1960/4885SLC1A2 1169/4885SLC1A1 1402/4885 |
| US-20120123161-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Modafinil by Asymmetric Oxidation | CYP2F1, SULT1A1, SULT2A1 | SLC1A3 1079/4885SLC1A2 497/4885SLC1A1 756/4885 |
| US-20130066111-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Modafinil by Asymmetric Oxidation | CYP2F1, SULT1A1, SULT2A1 | SLC1A3 1079/4885SLC1A2 497/4885SLC1A1 756/4885 |
| US-20050222257-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CYP2F1, SULT1A1, SULT2A1 | SLC1A3 1079/4885SLC1A2 497/4885SLC1A1 756/4885 |
| US-20060205706-A1 | Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation | SULT1A1, TST, SULT2A1 | SLC1A3 1960/4885SLC1A2 1169/4885SLC1A1 1402/4885 |
| US-20050080256-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | MAOA, CYP2F1, MAOB | SLC1A3 1115/4885SLC1A2 493/4885SLC1A1 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.