SCHEMBL17248337

SCHEMBL17248337

c1ccc2c(c1)oc1c(-n3c4ccccc4c4cc(-c5ccc6sc7ccccc7c6c5)ccc43)cccc12

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.36
PRKDC P78527 2/20 0.32
GPR3 P46089 1/20 0.32
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
PLA2G10 O15496 1/20 0.30
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15630680 0.98 ALOX5 (0.37) ALOX5PRKDCGPR3ESR1ESR2
SCHEMBL20633665 0.95 ALOX5 (0.33) ALOX5PRKDC
SCHEMBL22107496 0.93 PRKDC (0.33) ALOX5PRKDCGPR3ESR1ESR2
SCHEMBL22107003 0.92 PLA2G2A (0.34) PRKDCPLA2G10PLA2G2APLA2G4A
SCHEMBL26506953 0.92 PRKDC (0.39) ALOX5PRKDCGPR3ESR1ESR2
SCHEMBL11885217 0.91 PRKDC (0.37) ALOX5PRKDCESR1ESR2
SCHEMBL23737652 0.91 ALOX5 (0.34) ALOX5PRKDC
SCHEMBL25050785 0.91 ALOX5 (0.33) ALOX5PRKDC
SCHEMBL22107270 0.90 PLA2G2A (0.35) PRKDCGPR3PLA2G10PLA2G2APLA2G4A
SCHEMBL11885007 0.89 ALOX5 (0.43) ALOX5PRKDCPLA2G10PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10361378-B2 Organic electroluminescent device NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-23 US disclosed
US-9911924-B2 Material for organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
US-9911924-B2 Material for organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
EP-2933851-B1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL & SUMIKIN CHEM CO (JP) 2017-05-10 EP disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10361378-B2 Organic electroluminescent device ELF3, DDT, LEF1 ALOX5 1717/4885PRKDC 1748/4885GPR3 3910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.