Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NSD2 | O96028 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | GALK1 | P51570 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | S100A4 | P26447 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 5/20 | 0.45 |
| ▸ | CDC25A | P30304 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17249970 | 0.83 | MAPT (0.57) | HKDC1MAPTKMT2ANPSR1RAB9A | |
| SCHEMBL17249978 | 0.80 | CDC25A (0.59) | HKDC1MAPTKMT2ANPSR1RAB9A | |
| SCHEMBL10502055 | 0.77 | MAPT (0.70) | HKDC1MAPTKMT2ANPSR1RAB9A | |
| SCHEMBL17250098 | 0.77 | MAPT (0.56) | HKDC1MAPTKMT2ANPSR1RAB9A | |
| SCHEMBL17249963 | 0.77 | MAPT (0.56) | HKDC1MAPTKMT2ANPSR1RAB9A | |
| SCHEMBL29226600 | 0.76 | RAB9A (0.58) | HKDC1MAPTKMT2ANPSR1RAB9A | |
| SCHEMBL2466820 | 0.76 | NSD2 (0.71) | HKDC1MAPTKMT2ANPSR1RAB9A | |
| SCHEMBL17250420 | 0.74 | MAPK1 (0.50) | HKDC1MAPTKMT2ANPSR1RAB9A | |
| SCHEMBL12333959 | 0.71 | RAB9A (0.57) | HKDC1MAPTKMT2ANPSR1RAB9A | |
| SCHEMBL25706306 | 0.70 | RAB9A (0.51) | HKDC1MAPTKMT2ANPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015172076-A1 | NAPHTHAQUINONE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2015-11-12 | — | — | WO | disclosed |