Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NSD2 | O96028 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | GALK1 | P51570 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PLEC | Q15149 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466820 | 0.73 | NSD2 (0.71) | RAB9AHKDC1KDM4EMAPTLMNA | |
| SCHEMBL29226600 | 0.73 | RAB9A (0.58) | RAB9AHKDC1KDM4EMAPTLMNA | |
| SCHEMBL11037676 | 0.70 | MEN1 (0.55) | RAB9AKDM4EMAPTLMNANPSR1 | |
| SCHEMBL17249922 | 0.70 | HKDC1 (0.50) | RAB9AHKDC1KDM4EMAPTLMNA | |
| SCHEMBL11334587 | 0.69 | MEN1 (0.58) | RAB9AHKDC1KDM4EMAPTLMNA | |
| SCHEMBL12333959 | 0.69 | RAB9A (0.57) | RAB9AHKDC1KDM4EMAPTLMNA | |
| SCHEMBL9750769 | 0.68 | HKDC1 (0.60) | RAB9AHKDC1KDM4EMAPTLMNA | |
| SCHEMBL10195778 | 0.68 | MAPT (1.00) | RAB9AHKDC1KDM4EMAPTLMNA | |
| SCHEMBL19956897 | 0.67 | MAPKAPK2 (0.57) | RAB9AHKDC1KDM4EMAPTLMNA | |
| SCHEMBL2814457 | 0.67 | MAOA (0.57) | RAB9AHKDC1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180034-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING NAPHTHOQUINONE-BASED COMPOUND AND IMMUNE CHECKPOINT INHIBITOR AS ACTIVE INGREDIENTS | NADIANBIO Ltd. (KR) | 2023-05-17 | — | — | EP | disclosed |