Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426096 | 0.85 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL172707 | 0.85 | TAAR1 (0.35) | NFE2L2KDM4EALDH1A1ERN1SMN1; SMN2 | |
| SCHEMBL25544499 | 0.80 | NFE2L2 (0.37) | NFE2L2KDM4EALDH1A1ERN1SMN1; SMN2 | |
| SCHEMBL7184430 | 0.80 | ERN1 (0.52) | NFE2L2KDM4EALDH1A1ERN1SMN1; SMN2 | |
| SCHEMBL16962801 | 0.80 | ERN1 (0.38) | NFE2L2KDM4EALDH1A1ERN1SMN1; SMN2 | |
| SCHEMBL91337 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2TAAR1MEN1 | |
| SCHEMBL29700800 | 0.78 | ALDH1A1 (0.35) | KDM4EALDH1A1TAAR1GAACYP1A2 | |
| SCHEMBL29407303 | 0.78 | GABRA1 (0.41) | ALDH1A1SMN1; SMN2TAAR1 | |
| SCHEMBL9310181 | 0.78 | ALDH1A1 (0.35) | KDM4EALDH1A1TAAR1GAACYP1A2 | |
| SCHEMBL59712 | 0.78 | GABRA1 (0.41) | ALDH1A1SMN1; SMN2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |
| US-5326489-A | Sulfonated polymer | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0523300-B1 | Electrorheological fluids | NIPPON CATALYTIC CHEM IND (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0523300-A1 | Electrorheological fluids | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |