Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | MARS1 | P56192 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17252259 | 0.80 | NPY5R (0.36) | THRBHPGD | |
| SCHEMBL19957853 | 0.80 | NPY5R (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17252260 | 0.79 | RPA1 (0.40) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL19957852 | 0.79 | SCN9A (0.40) | MRGPRX4 | |
| SCHEMBL19957807 | 0.78 | NPY5R (0.35) | THRB | |
| SCHEMBL3687375 | 0.73 | KDM4E (0.47) | MARS1KDM4EHSD17B10ALDH1A1HTT | |
| SCHEMBL1663111 | 0.71 | KDM4E (0.49) | TTRKDM4EHSD17B10ALDH1A1APOBEC3A | |
| SCHEMBL3691646 | 0.71 | KDM4E (0.52) | TTRKDM4EHSD17B10ALDH1A1APOBEC3A | |
| SCHEMBL4910976 | 0.71 | HSD17B10 (0.46) | MARS1KDM4EHSD17B10ALDH1A1KMO | |
| SCHEMBL30261774 | 0.70 | JUN (0.42) | MARS1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3139743-B1 | PYRAZOLOPYRIDINE SULFONAMIDES AS NEMATICIDES | BAYER CROPSCIENCE AG (DE) | 2018-03-14 | — | — | EP | disclosed |
| US-20170088548-A1 | PYRAZOLOPYRIDINE SULFONAMIDES AS NEMATICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-30 | — | — | US | disclosed |
| US-20170088548-A1 | PYRAZOLOPYRIDINE SULFONAMIDES AS NEMATICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-30 | — | — | US | disclosed |
| WO-2015169776-A1 | PYRAZOLOPYRIDINE SULFONAMIDES AS NEMATICIDES | BAYER CROPSCIENCE AG (DE) | 2015-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088548-A1 | PYRAZOLOPYRIDINE SULFONAMIDES AS NEMATICIDES | NISCH, CATSPER1, KCNH1 | TTR 2842/4885MARS1 2456/4885KDM4E 2941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.