SCHEMBL1725484

SCHEMBL1725484

[C]1Cc2ccccc2[CH]N1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.33
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2948 0.64
SCHEMBL29539 0.64
SCHEMBL1289715 0.64
SCHEMBL19678 0.62
SCHEMBL20528826 0.62 TRPA1 (0.34) PARP1
SCHEMBL37705 0.62 PNMT (0.39) HTR2C
SCHEMBL28776095 0.62
SCHEMBL8343541 0.62 TRPA1 (0.34) PARP1
SCHEMBL19579719 0.60 HTR2C (0.48) PARP1HTR2C
SCHEMBL155336 0.60 PARP1 (0.39) PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070189970-A1 Contrast medium for thrombus formation ASTELLAS PHARMA INC. (JP) 2007-08-16 US claimed
EP-1719529-A1 CONTRAST MEDIUM FOR THROMBUS FORMATION Astellas Pharma Inc. (JP) 2006-11-08 EP claimed
EP-2404899-A1 Contrast medium for thrombus detection Astellas Pharma Inc. (JP) 2012-01-11 EP disclosed
US-20070189970-A1 Contrast medium for thrombus formation ASTELLAS PHARMA INC. (JP) 2007-08-16 US disclosed
EP-1719529-A1 CONTRAST MEDIUM FOR THROMBUS FORMATION Astellas Pharma Inc. (JP) 2006-11-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070189970-A1 Contrast medium for thrombus formation FGB, F13B, TFPI PARP1 4239/4885HTR2C 2785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.