Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | FOXO1 | Q12778 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17255210 | 0.89 | AMY1A (0.48) | AMY1AMAPTAPPFOXO1 | |
| SCHEMBL17255179 | 0.88 | MAPT (0.46) | AMY1AMAPTTP53APPPDGFRB | |
| SCHEMBL17255254 | 0.87 | MAPT (0.47) | AMY1AMAPTAPPFOXO1PDGFRB | |
| SCHEMBL17255233 | 0.86 | FOXO1 (0.46) | AMY1AMAPTFOXO1 | |
| SCHEMBL17255231 | 0.86 | MAPT (0.43) | AMY1AMAPTTP53APPFOXO1 | |
| SCHEMBL17255224 | 0.85 | FOXO1 (0.53) | AMY1AMAPTAPPFOXO1KDR | |
| SCHEMBL17255157 | 0.84 | RAB9A (0.56) | AMY1AMAPTFOXO1 | |
| SCHEMBL17268675 | 0.84 | AMY1A (0.43) | AMY1AAPPFOXO1 | |
| SCHEMBL17255252 | 0.84 | SMN1; SMN2 (0.41) | AMY1AMAPTAPPFOXO1 | |
| SCHEMBL17255203 | 0.83 | MAPT (0.41) | AMY1AMAPTTP53APPFOXO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-11-19 | — | — | US | claimed |
| EP-2944635-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2015-11-18 | — | — | EP | claimed |
| EP-2944635-B1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2018-11-28 | — | — | EP | disclosed |
| US-9951049-B2 | Pyrazole linked benzimidazole conjugates and a process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |
| US-9951049-B2 | Pyrazole linked benzimidazole conjugates and a process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-11-19 | — | — | US | disclosed |
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-11-19 | — | — | US | disclosed |
| EP-2944635-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2015-11-18 | — | — | EP | disclosed |
| EP-2944635-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2015-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | BRDT, MCL1, MGST3 | AMY1A 4542/4885MAPT 1962/4885TP53 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.