Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 7/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17255216 | 0.91 | RAB9A (0.49) | AMY1ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL17268713 | 0.91 | CBFB (0.37) | AMY1AFGFR1FGFR2FGFR3PDPK1 | |
| SCHEMBL17255334 | 0.88 | AMY1A (0.42) | AMY1AMAPTALDH1A1SMN1; SMN2RUNX1 | |
| SCHEMBL17255189 | 0.85 | GUSB (0.45) | AMY1ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL17255338 | 0.83 | AMY1A (0.43) | AMY1ANPC1RAB9AMAPTPDPK1 | |
| SCHEMBL17255340 | 0.83 | AMY1A (0.53) | AMY1ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL17255149 | 0.83 | NPBWR1 (0.46) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL17255232 | 0.83 | RAB9A (0.43) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL17255355 | 0.82 | TRPV1 (0.43) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL17268716 | 0.81 | AMY1A (0.37) | AMY1ANPC1RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-11-19 | — | — | US | claimed |
| EP-2944635-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2015-11-18 | — | — | EP | claimed |
| US-9951049-B2 | Pyrazole linked benzimidazole conjugates and a process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-11-19 | — | — | US | disclosed |
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-11-19 | — | — | US | disclosed |
| EP-2944635-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2015-11-18 | — | — | EP | disclosed |
| EP-2944635-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2015-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | BRDT, MCL1, MGST3 | AMY1A 4542/4885NPC1 4568/4885RAB9A 4061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.