Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17255679 | 0.86 | KDM4E (0.62) | KDM4EGAATSHREGFRMAPT | |
| SCHEMBL17255687 | 0.83 | KDM4E (0.62) | KDM4EGAATSHREGFRMAPT | |
| SCHEMBL2052349 | 0.79 | KDM4E (0.67) | KDM4EGAATSHRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4340036 | 0.78 | KDM4E (0.50) | KDM4EGAATSHREGFRMAPT | |
| Hydrochloric Acid SCHEMBL4340038 | 0.78 | KDM4E (0.50) | KDM4EGAATSHREGFRMAPT | |
| Phenol SCHEMBL4337822 | 0.76 | KDM4E (0.58) | KDM4EGAATSHRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4336653 | 0.76 | KDM4E (0.64) | KDM4EGAATSHREGFRMAPT | |
| Hydrochloric Acid SCHEMBL4336655 | 0.76 | KDM4E (0.64) | KDM4EGAATSHREGFRMAPT | |
| SCHEMBL15442244 | 0.74 | KDM4E (0.85) | KDM4EGAATSHREGFRMAPT | |
| SCHEMBL16911620 | 0.74 | KDM4E (0.59) | KDM4EGAATSHREGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2669274-B1 | TOPICAL ANTIFUNGAL AGENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2015-11-18 | — | — | EP | disclosed |