Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17255696 | 0.86 | KDM4E (0.58) | KDM4EGAATSHRMAPTEGFR | |
| SCHEMBL2052349 | 0.86 | KDM4E (0.67) | KDM4EGAATSHRMAPTCA12 | |
| SCHEMBL17255687 | 0.83 | KDM4E (0.62) | KDM4EGAATSHRMAPTEGFR | |
| SCHEMBL17255714 | 0.80 | KDM4E (0.58) | KDM4EGAATSHRMAPTSMN1; SMN2 | |
| Bicarbonate SCHEMBL17255684 | 0.80 | KDM4E (0.59) | KDM4EGAATSHRMAPTCA12 | |
| Phenol SCHEMBL4337822 | 0.76 | KDM4E (0.58) | KDM4EGAATSHRMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4336653 | 0.76 | KDM4E (0.64) | KDM4EGAATSHRMAPTEGFR | |
| Hydrochloric Acid SCHEMBL4336655 | 0.76 | KDM4E (0.64) | KDM4EGAATSHRMAPTEGFR | |
| SCHEMBL17255683 | 0.75 | KDM4E (0.66) | KDM4EGAATSHRMAPTCA12 | |
| SCHEMBL15442244 | 0.74 | KDM4E (0.85) | KDM4EGAATSHRMAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2669274-B1 | TOPICAL ANTIFUNGAL AGENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2015-11-18 | — | — | EP | claimed |