Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15442859 | 0.87 | MYC (0.55) | CA12CA1CA2CA9MYC | |
| SCHEMBL15442861 | 0.86 | MEN1 (0.51) | MYCLMNAALDH1A1KMT2AAR | |
| SCHEMBL16761057 | 0.83 | CA12 (0.50) | CA12CA1CA2CA9MYC | |
| SCHEMBL27993082 | 0.79 | CASP1 (0.47) | CA12CA1CA2CA9LMNA | |
| SCHEMBL15443094 | 0.78 | GAA (0.58) | CA12CA1CA2CA9MYC | |
| SCHEMBL16761056 | 0.76 | CA9 (0.40) | CA12CA1CA2CA9LMNA | |
| SCHEMBL15442468 | 0.76 | CA12 (0.40) | CA12CA1CA2CA9MYC | |
| SCHEMBL17255708 | 0.76 | LMNA (0.50) | CA12CA1CA2CA9LMNA | |
| SCHEMBL17255678 | 0.75 | KDM4E (0.47) | CA12CA1CA2CA9LMNA | |
| SCHEMBL27993294 | 0.73 | SMN1; SMN2 (0.44) | ALDH1A1KDM4EHPGDKMT2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2669274-B1 | TOPICAL ANTIFUNGAL AGENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2015-11-18 | — | — | EP | claimed |
| CN-104661661-A | External liquid preparation for resisting trichophytosis | MEIJI SEIKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |