Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16761056 | 0.81 | CA9 (0.40) | LMNACA12CA1CA2CA9 | |
| SCHEMBL15442468 | 0.81 | CA12 (0.40) | LMNACA12CA1CA2CA9 | |
| SCHEMBL27993082 | 0.81 | CASP1 (0.47) | LMNACA12CA1CA2CA9 | |
| SCHEMBL15442859 | 0.77 | MYC (0.55) | LMNACA12CA1CA2CA9 | |
| SCHEMBL28102000 | 0.76 | HSD17B10 (0.51) | LMNACA12CA1CA2CA9 | |
| SCHEMBL17255697 | 0.76 | CA12 (0.43) | LMNACA12CA1CA2CA9 | |
| SCHEMBL9662604 | 0.75 | LMNA (0.41) | LMNACA12CA1CA2CA9 | |
| SCHEMBL17255695 | 0.75 | KDM4E (0.66) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL27993294 | 0.75 | SMN1; SMN2 (0.44) | ALDH1A1TSHRTDP1SMN1; SMN2GAA | |
| SCHEMBL15443316 | 0.74 | POLB (0.44) | LMNAALDH1A1CYP3A4GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2669274-B1 | TOPICAL ANTIFUNGAL AGENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2015-11-18 | — | — | EP | claimed |