Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.68 |
| ▸ | DRD1 | P21728 | 1/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | CASR | P41180 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12964253 | 1.00 | CYP3A4 (0.68) | CYP3A4LMNACHRM2HTR1AADRA2A | |
| SCHEMBL12964248 | 1.00 | CYP3A4 (0.68) | CYP3A4LMNACHRM2HTR1AADRA2A | |
| Ammonia Solution, Strong SCHEMBL17257941 | 0.98 | CYP3A4 (0.66) | CYP3A4LMNACHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL27701535 | 0.98 | KMT2A (0.69) | CYP3A4LMNACHRM2HTR1AADRA2A | |
| SCHEMBL7029067 | 0.89 | CASR (0.56) | CYP3A4LMNACHRM2HTR1AADRA2A | |
| SCHEMBL24406703 | 0.89 | CYP3A4 (0.76) | CYP3A4LMNACHRM2HTR1AADRA2A | |
| SCHEMBL5471668 | 0.89 | CYP3A4 (0.76) | CYP3A4LMNACHRM2HTR1AADRA2A | |
| SCHEMBL3881700 | 0.89 | CYP3A4 (0.76) | CYP3A4LMNACHRM2HTR1AADRA2A | |
| SCHEMBL3881699 | 0.89 | CYP3A4 (0.76) | CYP3A4LMNACHRM2HTR1AADRA2A | |
| SCHEMBL13676409 | 0.88 | CYP3A4 (0.63) | CYP3A4LMNACHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177611-B1 | OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES | NUEVOLUTION AS (DK) | 2021-10-06 | — | — | EP | disclosed |
| US-10647701-B2 | 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | NOVARTIS AG (CH) | 2020-05-12 | — | — | US | disclosed |
| EP-3082805-B1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INST FOR DRUG DISCOVERY LLC (US) | 2020-02-05 | — | — | EP | disclosed |
| US-8835427-B2 | Fungicidal heterocyclic compounds | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-09-16 | — | — | US | disclosed |
| EP-2358709-B1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | DU PONT (US) | 2014-01-22 | — | — | EP | disclosed |
| US-8618137-B2 | Fungicidal heterocyclic compounds | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-12-31 | — | — | US | disclosed |
| US-8586611-B2 | Fungicidal carboxamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-11-19 | — | — | US | disclosed |
| EP-1948649-B1 | FUNGICIDAL CARBOXAMIDES | DU PONT (US) | 2013-06-26 | — | — | EP | disclosed |
| US-20120309752-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-06 | — | — | US | disclosed |
| US-20120093917-A1 | METNASE AND INTNASE INHIBITORS AND THEIR USE IN TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2012-04-19 | — | — | US | disclosed |
| CN-100482680-C | excitatory amino acid prodrugs | LILLY CO ELI (US) | 2009-04-29 | — | — | CN | disclosed |
| CN-101362793-A | Prodrugs of excitatory amino acids | LILLY CO ELI (US) | 2009-02-11 | — | — | CN | disclosed |
| US-7432239-B2 | Polyoxyalkylene compound and method for making | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES (US) | 2008-10-07 | — | — | US | disclosed |
| CN-101084236-A | excitatory amino acid prodrugs | LILLY CO ELI (US) | 2007-12-05 | — | — | CN | disclosed |
| CN-1181690-A | Herbicidal aza bisphosphonic acids and compsns. containing the same | ZENECA LTD (GB) | 1998-05-13 | — | — | CN | disclosed |
| EP-0576350-B1 | Branched alkylamino thiazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1997-10-29 | — | — | EP | disclosed |
| US-5464847-A | Moduators of corticotropin releasing factor | ELF SANOFI (FR) | 1995-11-07 | — | — | US | disclosed |
| EP-0576350-A1 | Branched alkylamino thiozole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-4958029-A | Process for the production of isoindoline derivatives, novel intermediates and process for their production | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0275064-A2 | Process for the production of isoindoline derivatives, novel intermediates and process for their production | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120093917-A1 | METNASE AND INTNASE INHIBITORS AND THEIR USE IN TREATING CANCER | RNASE1, DCLRE1B, FEN1 | CYP3A4 3920/4885LMNA 1247/4885CHRM2 4883/4885 |
| US-20120309752-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | CYP1B1, NOX3, CYP1A1 | CYP3A4 68/4885LMNA 3106/4885CHRM2 95/4885 |
| US-10647701-B2 | 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | XDH, H1-0, RXFP1 | CYP3A4 162/4885LMNA 731/4885CHRM2 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.