Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28491401 | 1.00 | CA2 (0.56) | CA2CA1MAPK1ZDHHC7GAA | |
| SCHEMBL28497772 | 1.00 | CA2 (0.56) | CA2CA1MAPK1ZDHHC7GAA | |
| SCHEMBL585232 | 1.00 | CA2 (0.56) | CA2CA1MAPK1ZDHHC7GAA | |
| SCHEMBL190801 | 1.00 | CA2 (0.56) | CA2CA1MAPK1ZDHHC7GAA | |
| Hydrochloric Acid SCHEMBL27586576 | 0.98 | CA2 (0.55) | CA2CA1MAPK1ZDHHC7GAA | |
| Hydrochloric Acid SCHEMBL27649377 | 0.98 | CA2 (0.55) | CA2CA1MAPK1ZDHHC7GAA | |
| Hydrochloric Acid SCHEMBL27649378 | 0.98 | CA2 (0.55) | CA2CA1MAPK1ZDHHC7GAA | |
| Ethane SCHEMBL28789613 | 0.98 | CA2 (0.55) | CA2CA1MAPK1ZDHHC7GAA | |
| SCHEMBL3836421 | 0.98 | CA2 (0.58) | CA2CA1MAPK1ZDHHC7GAA | |
| Oxalic Acid SCHEMBL28618643 | 0.95 | CA2 (0.51) | CA2CA1MAPK1ZDHHC7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135921-A | Dihydropyrimidine-spiro derivative and preparation method and application thereof | 山东大学 | 2021-07-20 | — | — | CN | claimed |
| CN-107873023-A | 3-alkyl-4-amido-bicyclo [4, 5, 0] hydroxamic acids as HDAC inhibitors | 福马治疗股份有限公司 | 2018-04-03 | — | — | CN | claimed |
| CN-104710408-A | Chiral cis-imidazolines | HOFFMANN LA ROCHE | 2015-06-17 | — | — | CN | claimed |
| CN-101821251-A | Chiral cis-imidazolines | HOFFMANN LA ROCHE | 2010-09-01 | — | — | CN | claimed |
| CN-119894895-A | IRAK4 degradation agent and application thereof | 领泰生物医药(绍兴)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119233974-A | Indolone derivative and application thereof | 康百达（四川）生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-113412259-B | Difunctional compounds for degrading BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-114080384-B | Herbicidal cyclohexanedione derivatives | 先正达农作物保护股份公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-116323562-B | Compounds with kinase inhibitory activity | 上海赛岚生物科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118206550-A | SHP2 inhibitor and application thereof | 江苏威凯尔医药科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118103074-A | Cytotoxic targeting chimeras for CCR2 expressing cells | 葛兰素史克知识产权发展有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-114728938-B | Tetrahydroisoquinoline spiro compounds as PRMT5 inhibitors | 南京再明医药有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-101687822-A | Di(arylamino)aryl compound | ASTELLAS PHARMA INC | 2010-03-31 | — | — | CN | disclosed |
| CN-101305005-A | Novel diazaspiroalkanes and their use for treatment of CCR8 mediated diseases | ASTRAZENECA AB (SE) | 2008-11-12 | — | — | CN | disclosed |
| CN-101163696-A | Histone deacetylase inhibitors | CHROMA THERAPEUTICS LTD (GB) | 2008-04-16 | — | — | CN | disclosed |
| CN-101155811-A | Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases | ASTRAZENECA AB (SE) | 2008-04-02 | — | — | CN | disclosed |
| CN-101155812-A | Novel diazaspiroalkanes and their use to treat CCR8 mediated diseases | ASTRAZENECA AB (SE) | 2008-04-02 | — | — | CN | disclosed |
| CN-101155810-A | Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases | ASTRAZENECA AB (SE) | 2008-04-02 | — | — | CN | disclosed |
| CN-1898239-A | Novel diazaspiroalkanes and their use in the treatment of CCR8 mediated diseases | ASTRAZENECA AB (SE) | 2007-01-17 | — | — | CN | disclosed |
| WO-2003053941-A2 | BARBITURIC ACID DERIVATIVES AS INHIBITORS OF TNF-ALPHA CONVERTING ENZYME (TACE) AND/OR MATRIX METALLOPROTEINASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |