Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL28818849 | 0.98 | CA2 (0.53) | CA2CA1MAPK1GRIK1GRIK2 | |
| SCHEMBL1725609 | 0.95 | CA2 (0.56) | CA2CA1MAPK1GRIK1GRIK2 | |
| SCHEMBL190801 | 0.95 | CA2 (0.56) | CA2CA1MAPK1GRIK1GRIK2 | |
| SCHEMBL28497772 | 0.95 | CA2 (0.56) | CA2CA1MAPK1GRIK1GRIK2 | |
| SCHEMBL585232 | 0.95 | CA2 (0.56) | CA2CA1MAPK1GRIK1GRIK2 | |
| SCHEMBL28491401 | 0.95 | CA2 (0.56) | CA2CA1MAPK1GRIK1GRIK2 | |
| Ethane SCHEMBL28789613 | 0.93 | CA2 (0.55) | CA2CA1MAPK1GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL27649377 | 0.93 | CA2 (0.55) | CA2CA1MAPK1GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL27586576 | 0.93 | CA2 (0.55) | CA2CA1MAPK1GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL27649378 | 0.93 | CA2 (0.55) | CA2CA1MAPK1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113278021-B | Preparation method of 1, 7-diazaspiro [3.5] nonane-7-tert-butyl formate and oxalate thereof | 天津全和诚科技有限责任公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-113278021-A | Preparation method of 1, 7-diazaspiro [3.5] nonane-7-tert-butyl formate and oxalate thereof | 天津全和诚科技有限责任公司 | 2021-08-20 | — | — | CN | disclosed |