Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28491401 | 1.00 | CA2 (0.56) | CA2CA1MAPK1ZDHHC7GAA | |
| SCHEMBL28497772 | 1.00 | CA2 (0.56) | CA2CA1MAPK1ZDHHC7GAA | |
| SCHEMBL1725609 | 1.00 | CA2 (0.56) | CA2CA1MAPK1ZDHHC7GAA | |
| SCHEMBL190801 | 1.00 | CA2 (0.56) | CA2CA1MAPK1ZDHHC7GAA | |
| Hydrochloric Acid SCHEMBL27586576 | 0.98 | CA2 (0.55) | CA2CA1MAPK1ZDHHC7GAA | |
| Hydrochloric Acid SCHEMBL27649377 | 0.98 | CA2 (0.55) | CA2CA1MAPK1ZDHHC7GAA | |
| Hydrochloric Acid SCHEMBL27649378 | 0.98 | CA2 (0.55) | CA2CA1MAPK1ZDHHC7GAA | |
| Ethane SCHEMBL28789613 | 0.98 | CA2 (0.55) | CA2CA1MAPK1ZDHHC7GAA | |
| SCHEMBL3836421 | 0.98 | CA2 (0.58) | CA2CA1MAPK1ZDHHC7GAA | |
| Oxalic Acid SCHEMBL28618643 | 0.95 | CA2 (0.51) | CA2CA1MAPK1ZDHHC7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118056816-A | Pyrazole-3-ketone derivative, and preparation method and application thereof | 沈阳药科大学 | 2024-05-21 | — | — | CN | claimed |
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | claimed |
| CN-115989223-A | Methods and compositions for targeting Tregs using CCR8 inhibitors | 南京艾美斐生物医药科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115551831-A | CYP11A1 inhibitor | 奥赖恩公司 | 2022-12-30 | — | — | CN | claimed |
| CN-115315424-A | 2-methyl-aza-quinazolines | 拜耳公司 | 2022-11-08 | — | — | CN | claimed |
| CN-113278021-B | Preparation method of 1, 7-diazaspiro [3.5] nonane-7-tert-butyl formate and oxalate thereof | 天津全和诚科技有限责任公司 | 2022-09-23 | — | — | CN | claimed |
| CN-113278021-A | Preparation method of 1, 7-diazaspiro [3.5] nonane-7-tert-butyl formate and oxalate thereof | 天津全和诚科技有限责任公司 | 2021-08-20 | — | — | CN | claimed |
| CN-113214256-A | Synthesis method of 1, 7-diazaspiro [3.5] nonane-7-tert-butyl formate | 上海合全药业股份有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-105732638-B | A kind of bruton's tyrosine kinase inhibitor with loop coil or caged scaffold and preparation method thereof | 成都倍特药业有限公司 | 2018-01-30 | — | — | CN | claimed |
| CN-105732638-A | Bruton tyrosine kinase inhibitor with spiro or bridge ring structure and preparation method thereof | 成都倍特药业有限公司 | 2016-07-06 | — | — | CN | claimed |
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118344370-A | Isoindolinone and indazole compounds for EGFR degradation | C4医药公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118302426-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118284608-A | Compounds as BCL-2 inhibitors | 重庆复创医药研究有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118215661-A | Compounds as BCL-2 inhibitors | 重庆复创医药研究有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-1399639-A | Novel oxabispidine compounds for the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2003-02-26 | — | — | CN | disclosed |
| CN-1370166-A | Novel bispidine compounds useful in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2002-09-18 | — | — | CN | disclosed |
| CN-1290167-A | Dried or frozen pharmaceutical prepartion containing class III antiarrhythmic compound | ASTRAZENECA AB (SE) | 2001-04-04 | — | — | CN | disclosed |
| CN-1284956-A | Novel bispidine antiarrhythmic compounds | ASTRA ZENECA AKTIEBOLAG (SE) | 2001-02-21 | — | — | CN | disclosed |
| CN-1275124-A | Phthalazine derivatives and remedies for erectile dysfunction | EISAI CO LTD (JP) | 2000-11-29 | — | — | CN | disclosed |