Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.40 |
| ▸ | ESR1 | P03372 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4865359 | 0.83 | ESR2 (0.42) | ESR2ESR1KMT2AMEN1GAA | |
| SCHEMBL1725847 | 0.75 | MAPT (0.41) | KMT2AMEN1GAAHSD17B10MAPT | |
| SCHEMBL4861999 | 0.70 | POLB (0.38) | ESR2ESR1KMT2AMEN1GAA | |
| SCHEMBL29358275 | 0.69 | TRPA1 (0.45) | ESR2ESR1KMT2AMEN1HSD17B10 | |
| SCHEMBL12737774 | 0.69 | L3MBTL1 (0.55) | KMT2AMEN1GAAHSD17B10MAPT | |
| Orthocresol SCHEMBL28401339 | 0.68 | TRPA1 (0.41) | ESR2ESR1KMT2AMEN1GAA | |
| SCHEMBL30833366 | 0.68 | IDO1 (0.46) | ESR2ESR1KMT2AMEN1GAA | |
| SCHEMBL1101882 | 0.67 | CYP1A2 (0.68) | ESR2ESR1KMT2AMEN1GAA | |
| SCHEMBL272850 | 0.66 | INPPL1 (0.43) | KMT2AMEN1GAAHSD17B10MAPT | |
| SCHEMBL2220467 | 0.66 | INPPL1 (0.59) | KMT2AGAAHSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008513585-A | — | — | 2008-05-01 | — | — | JP | claimed |
| EP-1791850-A1 | 1,4-HYDROQUINONE FUNCTIONALIZED PHOSPHINATES AND PHOSPHONATES | CHEMTURA CORPORATION (US) | 2007-06-06 | — | — | EP | claimed |
| US-20060099458-A1 | 1, 4-Hydroquinone functionalized phosphinates and phosphonates | HANSON MARK V | 2006-05-11 | — | — | US | claimed |
| WO-2006034445-A1 | 1,4-HYDROQUINONE FUNCTIONALIZED PHOSPHYNATES AND PHOSPHONATES | CHEMTURA CORPORATION (US) | 2006-03-30 | — | — | WO | claimed |