Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 6/20 | 0.32 |
| ▸ | PPARD | Q03181 | 6/20 | 0.32 |
| ▸ | PPARA | Q07869 | 6/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786441 | 1.00 | TSHR (0.41) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL7712357 | 1.00 | TSHR (0.41) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL2336676 | 1.00 | TSHR (0.41) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL7712167 | 1.00 | TSHR (0.41) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL2026151 | 0.96 | LMNA (0.38) | TSHRLMNANFKB1PMP22CES2 | |
| SCHEMBL8781415 | 0.87 | — | — | |
| SCHEMBL3777730 | 0.84 | CES2 (0.57) | TSHRGPR84CES2CES1FFAR1 | |
| SCHEMBL422550 | 0.84 | TSHR (0.33) | TSHRLMNANFKB1PMP22 | |
| SCHEMBL7749105 | 0.84 | CES2 (0.57) | TSHRGPR84CES2CES1FFAR1 | |
| SCHEMBL7743611 | 0.84 | CES2 (0.57) | TSHRGPR84CES2CES1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593234-B2 | Rubber composition having intramolecular double bond | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2017-03-14 | — | — | US | claimed |
| US-20150329708-A1 | RUBBER COMPOSITION HAVING INTRAMOLECULAR DOUBLE BOND | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2015-11-19 | — | — | US | claimed |
| US-9593234-B2 | Rubber composition having intramolecular double bond | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2017-03-14 | — | — | US | disclosed |
| US-20150329708-A1 | RUBBER COMPOSITION HAVING INTRAMOLECULAR DOUBLE BOND | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2015-11-19 | — | — | US | disclosed |