Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 6/20 | 0.32 |
| ▸ | PPARD | Q03181 | 6/20 | 0.32 |
| ▸ | PPARA | Q07869 | 6/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786441 | 1.00 | TSHR (0.41) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL7712357 | 1.00 | TSHR (0.41) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL17259074 | 1.00 | TSHR (0.41) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL2336676 | 1.00 | TSHR (0.41) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL2026151 | 0.96 | LMNA (0.38) | TSHRLMNANFKB1PMP22CES2 | |
| SCHEMBL8781415 | 0.87 | — | — | |
| SCHEMBL3777730 | 0.84 | CES2 (0.57) | TSHRGPR84CES2CES1FFAR1 | |
| SCHEMBL422550 | 0.84 | TSHR (0.33) | TSHRLMNANFKB1PMP22 | |
| SCHEMBL7749105 | 0.84 | CES2 (0.57) | TSHRGPR84CES2CES1FFAR1 | |
| SCHEMBL7743611 | 0.84 | CES2 (0.57) | TSHRGPR84CES2CES1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309434-B1 | PROCESS FOR DECOLORIZING OF RESINOUS POLYMERS | FINA RESEARCH S.A. (BE) | 1992-09-02 | — | — | EP | claimed |
| US-4877863-A | TREATMENT WITH THIOCARBOXYLIC ACID | LABOFINA, S.A. (BE) | 1989-10-31 | — | — | US | claimed |
| EP-0309434-A1 | Process for decolorizing of resinous polymers | FINA RESEARCH S.A. (BE) | 1989-03-29 | — | — | EP | claimed |
| CN-102256938-A | Thioic acids as building blocks for polythioesters | DSM IP ASSETS BV | 2011-11-23 | — | — | CN | disclosed |
| CN-101258183-B | Polymers comprising thioester bonds | DSM IP ASSETS BV | 2011-01-26 | — | — | CN | disclosed |
| CN-101258183-A | Polymers comprising thioester bonds | DSM IP ASSETS BV (NL) | 2008-09-03 | — | — | CN | disclosed |
| US-6369269-B2 | Thiol and sulfur-containing O-(meth)acrylate compounds and use thereof | MITSUI CHEMICALS, INC. (JP) | 2002-04-09 | — | — | US | disclosed |
| US-20010044555-A1 | Thiol and sulfur-containing O-(meth)acrylate counpounds and use thereof | KOBAYASHI SEIICHI (JP) | 2001-11-22 | — | — | US | disclosed |
| US-6265510-B1 | OPTICS; LENSES | MITSUI CHEMICALS, INC. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0810210-B1 | Thiol and sulfur-containing o-(meth)acrylate compounds and use thereof | MITSUI CHEMICALS INC (JP) | 2001-01-10 | — | — | EP | disclosed |
| US-6114485-A | STARTING MATERIAL FOR A RESIN COMPOSITION USED IN OPTICAL APPLICATIONS SUCH AS A LENS | MITSUI CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5916987-A | OPTICAL RESIN; LENSES | MITSUI CHEMICALS, INC. (JP) | 1999-06-29 | — | — | US | disclosed |
| EP-0810210-A2 | Thiol and sulfur-containing o-(meth)acrylate compounds and use thereof | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-12-03 | — | — | EP | disclosed |
| EP-0636654-B1 | Block copolymer composition, a process for its preparation and a hot melt adhesive comprising said composition | SHELL INT RESEARCH (NL) | 1997-10-01 | — | — | EP | disclosed |
| EP-0636654-A1 | Block copolymer composition, a process for its preparation and a hot melt adhesive comprising said composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-02-01 | — | — | EP | disclosed |
| US-4877863-A | TREATMENT WITH THIOCARBOXYLIC ACID | LABOFINA, S.A. (BE) | 1989-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044555-A1 | Thiol and sulfur-containing O-(meth)acrylate counpounds and use thereof | MSRB3, BHMT2, HBS1L | TSHR 1745/4885LMNA 4236/4885NFKB1 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.