Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28118000 | 1.00 | — | — | |
| SCHEMBL9336269 | 1.00 | TSHR (0.33) | TSHRLMNANFKB1PMP22 | |
| SCHEMBL20588841 | 0.88 | — | — | |
| SCHEMBL17259074 | 0.84 | TSHR (0.41) | TSHRLMNANFKB1PMP22 | |
| SCHEMBL7712167 | 0.84 | TSHR (0.41) | TSHRLMNANFKB1PMP22 | |
| SCHEMBL7712357 | 0.84 | TSHR (0.41) | TSHRLMNANFKB1PMP22 | |
| SCHEMBL2786441 | 0.84 | TSHR (0.41) | TSHRLMNANFKB1PMP22 | |
| SCHEMBL2336676 | 0.84 | TSHR (0.41) | TSHRLMNANFKB1PMP22 | |
| SCHEMBL2026151 | 0.80 | LMNA (0.38) | TSHRLMNANFKB1PMP22 | |
| SCHEMBL23297342 | 0.74 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158421-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2024-05-16 | — | — | US | disclosed |
| US-11691995-B2 | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-07-04 | — | — | US | disclosed |
| EP-3556401-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | The University of North Carolina at Chapel Hill (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-2669269-B1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2019-05-22 | — | — | EP | disclosed |
| US-9403851-B2 | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2016-08-02 | — | — | US | disclosed |
| US-9403852-B2 | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2016-08-02 | — | — | US | disclosed |
| US-20160060279-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2016-03-03 | — | — | US | disclosed |
| US-20150182543-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2015-07-02 | — | — | US | disclosed |
| US-8962029-B2 | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2015-02-24 | — | — | US | disclosed |
| US-8956658-B2 | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2015-02-17 | — | — | US | disclosed |
| US-20140058124-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140005426-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-01-02 | — | — | US | disclosed |
| EP-2669269-A2 | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications | The University of North Carolina At Chapel Hill (US) | 2013-12-04 | — | — | EP | disclosed |
| US-8282967-B2 | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-10-09 | — | — | US | disclosed |
| US-20120034169-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-02-09 | — | — | US | disclosed |
| US-20120021055-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-01-26 | — | — | US | disclosed |
| US-20090214618-A1 | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2009-08-27 | — | — | US | disclosed |
| EP-1888510-A2 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | The University of North Carolina at Chapel Hill (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006128121-A2 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691995-B2 | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications | NOS2, NOS3, NOS1 | TSHR 673/4885LMNA 2261/4885NFKB1 1016/4885 |
| US-20090214618-A1 | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications | NOS2, NOS3, NOS1 | TSHR 673/4885LMNA 2261/4885NFKB1 1016/4885 |
| US-20240158421-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | NOS2, NOS3, NOS1 | TSHR 673/4885LMNA 2261/4885NFKB1 1016/4885 |
| US-20120034169-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | NOS2, NOS3, NOS1 | TSHR 673/4885LMNA 2261/4885NFKB1 1016/4885 |
| US-20120021055-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | NOS2, NOS3, NOS1 | TSHR 673/4885LMNA 2261/4885NFKB1 1016/4885 |
| US-20140058124-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | NOS2, NOS3, NOS1 | TSHR 673/4885LMNA 2261/4885NFKB1 1016/4885 |
| US-20150182543-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | NOS2, NOS3, NOS1 | TSHR 673/4885LMNA 2261/4885NFKB1 1016/4885 |
| US-20160060279-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | NOS2, NOS3, NOS1 | TSHR 673/4885LMNA 2261/4885NFKB1 1016/4885 |
| US-20140005426-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | NOS2, NOS3, NOS1 | TSHR 673/4885LMNA 2261/4885NFKB1 1016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.