Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095666 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TP53 | |
| SCHEMBL2692088 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TP53 | |
| SCHEMBL109401 | 0.90 | ALDH1A1 (0.44) | ALDH1A1TP53 | |
| SCHEMBL30420061 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TP53 | |
| SCHEMBL11132848 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TP53 | |
| SCHEMBL11795298 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TP53 | |
| SCHEMBL11677357 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TP53 | |
| SCHEMBL8646213 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TP53 | |
| SCHEMBL1276455 | 0.86 | — | — | |
| SCHEMBL11069638 | 0.85 | THRB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144064-B1 | SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2021-07-28 | — | — | EP | disclosed |
| EP-3553068-B1 | YDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL IP AMERICA INC (US) | 2021-04-28 | — | — | EP | disclosed |
| EP-3285582-B1 | PHOSPHATE-SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME (US) | 2020-11-11 | — | — | EP | disclosed |
| EP-3553068-A1 | HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL-IP America Inc. (US) | 2019-10-16 | — | — | EP | disclosed |
| EP-2909218-B1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL IP AMERICA INC (US) | 2019-07-10 | — | — | EP | disclosed |
| EP-3377596-A1 | SELECTIVE HYDROGENATION USING A FLOW INDEX | Chevron Phillips Chemical Company LP (US) | 2018-09-26 | — | — | EP | disclosed |
| US-10081647-B2 | Phosphate substituted quinolizine derivatives useful as HIV integrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-09-25 | — | — | US | disclosed |
| US-20180148260-A1 | Selective Hydrogenation Using a Flow Index | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2018-05-31 | — | — | US | disclosed |
| US-9914676-B2 | Selective hydrogenation using a flow index | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2018-03-13 | — | — | US | disclosed |
| EP-3285582-A1 | PHOSPHATE-SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2018-02-28 | — | — | EP | disclosed |
| US-8981042-B2 | Cycloaliphatic polyphosphite polymer stabilizers | DOVER CHEMICAL CORPORATION (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140378590-A1 | CYCLOALIPHATIC POLYPHOSPHITE | DOVER CHEMICAL CORPORATION (US) | 2014-12-25 | — | — | US | disclosed |
| US-20140378564-A1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL-IP AMERICA INC. | 2014-12-25 | — | — | US | disclosed |
| WO-2014062313-A1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL-IP AMERICA INC. (US) | 2014-04-24 | — | — | WO | disclosed |
| US-20140107383-A1 | Selective Hydrogenation Catalyst and Methods of Making and Using Same | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-04-17 | — | — | US | disclosed |
| US-8633127-B2 | Selective hydrogenation catalyst and methods of making and using same | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-01-21 | — | — | US | disclosed |
| CN-102341175-A | Selective hydrogenation catalyst and methods of making and using same | CHEVRON PHILLIPS CHEMICAL CO | 2012-02-01 | — | — | CN | disclosed |
| EP-2403642-A2 | SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME | Chevron Phillips Chemical Company LP (US) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010101736-A2 | SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2010-09-10 | — | — | WO | disclosed |
| US-20100228065-A1 | Selective Hydrogenation Catalyst and Methods of Making and Using Same | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10081647-B2 | Phosphate substituted quinolizine derivatives useful as HIV integrase inhibitors | TYMP, RPIA, NQO2 | ALDH1A1 2491/4885TP53 1251/4885 |
| US-20140378564-A1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | PFAS, PFKFB2, PFKFB1 | ALDH1A1 3447/4885TP53 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.